| Type | Description |
|---|---|
| Definition | small nuclear ribonucleoprotein polypeptide E |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 13:12:00 | Study reports de novo heterozygous missense mutation within the SNRPE gene disturbing appropriate spatiotemporal gene expression in the brain through aberrant mRNA splicing, and likely to cause the microcephaly phenotype. | 31671093 |
| 2013-06-29 12:03:00 | Overexpression of SNRPE is associated with highly aggressive breast cancers. | 23358685 |
| 2013-03-16 12:23:00 | Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex | 23246290 |
| 2010-01-21 00:00:00 | growth arrest by SmE directly correlates with the reduction of cyclin E, CDK2, CDC25C and CDC2 expression, and up-regulation of p27Kip | 18208561 |
| 2010-01-21 00:00:00 | In the SME intron, the position of the branchpoint A residue within the region base paired with U12 differs from that in P120 and XTF. | 12022225 |
| Type | IDs |
|---|---|
| Synonymous | HYPT11, SME, Sm-E, snRNP-E |
| Gene |
UniProtKB-ID:
RUXE_HUMAN
UniprotKB:
P62304
UniParc:
UPI0000029B34
EMBL:
M37716,
AK312130,
M21253,
BC002639,
BC090951,
M21258,
X12466,
CH471067,
M15919
Ensembl:
ENSG00000182004
KO:
hsa:6635
|
| Nucleutide sequences |
EMBL-CDS:
CAA31007.1,
AAH90951.1,
AAH02639.1,
AAA90926.1,
EAW91494.1,
AAB59365.1,
AAA36621.1,
BAG35066.1
Ensembl_TRS:
ENST00000414487
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000400591
RefSeq:
NP_001315567.1,
NP_001291393.1,
NP_001315566.1,
NP_003085.1
|
| Others |
UniRef100:
UniRef100_P62304
UniRef90:
UniRef90_P62304
UniRef50:
UniRef50_P62304
UniGene:
Hs.334612,
Hs.654418
CCDS:
CCDS30979.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员