| Type | Description |
|---|---|
| Definition | ATPase, H+ transporting, lysosomal V1 subunit C1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 12:33:00 | results showed that adneno-associated virus-mediated Atp6v1c1 knockdown in periapical tissues slowed endodontic disease progression, prevented bone erosion, and alleviated inflammation in the periapical tissues and periodontal ligament potentially through regulation of toll-like receptor signaling | 31104818 |
| 2019-06-08 11:52:00 | MIR29a plays an important role during the trans-differentiation of Activated hepatic stellate cells in the resolution of liver fibrosis, in part, through regulation of ATP6V1C1. | 30781750 |
| 2016-05-21 13:03:00 | Atp6v1c1 knockdown gene therapy mediated by AAV-shRNA-Atp6v1c1 is a promising novel therapeutic approach for the treatment of bone erosion and inflammatory related diseases, such as periodontitis and rheumatoid arthritis. | 26274612 |
| 2014-03-29 12:20:00 | Silencing of atp6v1c1 prevents breast cancer growth and bone metastasis. | 24155661 |
| 2010-01-21 00:00:00 | Study demonstrates that Atp6v1c1 is an essential component of the osteoclast proton pump at the osteoclast ruffled border and that it may regulate F-actin ring formation in osteoclast activation. | 18657050 |
| Type | IDs |
|---|---|
| Synonymous | 1700025B18Rik, U13839 |
| Gene |
UniProtKB-ID:
VATC1_MOUSE
UniprotKB:
Q9Z1G3
UniParc:
UPI00000020E3
EMBL:
AB088407,
AK075779,
AK151237,
U13839,
BC010217
Ensembl:
ENSMUSG00000022295,
ENSMUSG00000116394
KO:
mmu:66335
|
| Nucleutide sequences |
EMBL-CDS:
AAC83084.1,
BAC35953.1,
AAH10217.1,
BAC57953.1,
BAE30229.1
Ensembl_TRS:
ENSMUST00000022904,
ENSMUST00000229037
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022904,
ENSMUSP00000155467
RefSeq:
NP_079770.2,
XP_036015431.1
|
| Others |
UniRef100:
UniRef100_Q9Z1G3
UniRef90:
UniRef90_P21283
UniRef50:
UniRef50_P21283
UniGene:
Mm.276618
CCDS:
CCDS27439.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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