| Type | Description |
|---|---|
| Definition | SMAD specific E3 ubiquitin protein ligase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:57:00 | The Effects of WW2/WW3 Domains of Smurf2 Molecule on CD4+CD25+/CD4+ Proportion in Spleen of 4T1 Tumor Bearing BALB/c Mice. | 32306719 |
| 2020-02-15 10:46:00 | Smurf2 negatively regulates MOR1 activity by reducing its stability in lung epithelial cells. | 30758996 |
| 2019-07-20 11:00:00 | although conventional Smurf2 double knockout mice are early embryonic lethal, Cre-mediated recombination in mouse embryonic fibroblasts results in Smurf2 knockout cells that show it has roles in regulating many different signaling pathways and in genomic stability, cell polarity, tissue homeostasis and carcinogenesis | 29805305 |
| 2018-12-01 10:09:00 | Data suggest that Smad-specific E3 ubiquitin ligase 2 (SMURF2)-mediated SMAD3 protein (SMAD3) monoubiquitination interferes with the formation of a SMAD3-vitamin D receptor (VDR) complex. | 28216630 |
| 2017-09-30 13:38:00 | Results identified Smurf2 as an essential regulator of Topo IIalpha, providing novel insights into its control and into the suggested tumor-suppressor functions of Smurf2. | 28611047 |
| Type | IDs |
|---|---|
| Synonymous | 2810411E22Rik, AI558114, AI649275 |
| Gene |
UniProtKB-ID:
SMUF2_MOUSE,
Q9CSE3_MOUSE
UniprotKB:
A2A5Z6,
Q9CSE3
UniParc:
UPI00001E6896,
UPI000059DD88,
UPI00000215BB
EMBL:
AK013082,
CH466558,
BC138788,
AL593847,
BC138786,
AY685230
Ensembl:
ENSMUSG00000018363
KO:
mmu:66313
|
| Nucleutide sequences |
EMBL-CDS:
AAV87906.1,
AAI38789.1,
AAI38787.1,
EDL34316.1,
BAB28637.1
Ensembl_TRS:
ENSMUST00000092517,
ENSMUST00000103067,
ENSMUST00000167787
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000090177,
ENSMUSP00000099356,
ENSMUSP00000129269
RefSeq:
XP_006533999.1,
XP_036012789.1,
NP_001349823.1,
NP_079757.2,
XP_036012790.1
|
| Others |
UniRef100:
UniRef100_A2A5Z6,
UniRef100_A0A6P7RHY7
UniRef90:
UniRef90_A2A5Z6,
UniRef90_A0A6P7RHY7
UniRef50:
UniRef50_A2A5Z6,
UniRef50_A9JRZ0
UniGene:
Mm.340955
CCDS:
CCDS25564.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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