| Type | Description |
|---|---|
| Definition | family with sequence similarity 3, member A |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:31:00 | FAM3A attenuates IL-1beta-induced chondrocyte apoptosis through activating the pro-survival PI3K/Akt/mTOR pathway. | 31208715 |
| 2019-11-30 12:14:00 | our data demonstrate that FAM3A positively regulates angiogenesis through activation of VEGFA transcription, suggesting that FAM3A may constitute a novel molecular therapeutic target for ischaemic vascular disease. | 31000420 |
| 2019-05-25 11:36:00 | Study identified Fam3a, a cytokine-like protein, as a major Stat3 downstream effector in muscle stem cells and demonstrated that Fam3a is required for muscle stem cell commitment and skeletal muscle development. These findings indicate that Fam3a is a Stat3-regulated secreted factor that promotes muscle stem cell oxidative metabolism and differentiation. | 30996264 |
| 2018-04-28 11:08:00 | FAM3A protects against liver IRI by activating Akt survival pathways, repressing inflammation and attenuating oxidative stress. Moreover, the protective effects of PPARgamma agonist(s) on liver IRI are dependent on FAM3A-ATP-Akt pathway. | 28562339 |
| 2018-04-14 10:48:00 | FAM3A enhances the adipogenesis of preadipocytes by activating ATP-P2 receptor-Akt pathway. Under obese condition, a decrease in FAM3A expression in adipose tissues plays important roles in the development of adipose dysfunction and type 2 diabetes. | 28515350 |
| Type | IDs |
|---|---|
| Synonymous | 1810037C20Rik |
| Gene |
UniProtKB-ID:
FAM3A_MOUSE,
A0A158SIT7_MOUSE
UniprotKB:
Q9D8T0,
A0A158SIT7
UniParc:
UPI0000027619
EMBL:
AK007715,
BC069871,
AL807376
Ensembl:
ENSMUSG00000031399
KO:
mmu:66294
|
| Nucleutide sequences |
EMBL-CDS:
AAH69871.1,
BAB25208.1,
CAM24352.1
Gene_ORFName:
RP23-436K3.15-001
Ensembl_TRS:
ENSMUST00000015427,
ENSMUST00000114143,
ENSMUST00000114142
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109778,
ENSMUSP00000109779,
ENSMUSP00000015427
RefSeq:
NP_001300654.1,
NP_001366110.1,
NP_079749.1,
XP_036017966.1,
XP_011245962.1,
NP_001366111.1
|
| Others |
UniRef100:
UniRef100_Q9D8T0
UniRef90:
UniRef90_Q9D8T0
UniRef50:
UniRef50_Q6GQC1
UniGene:
Mm.166485
CCDS:
CCDS41022.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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