| Type | Description |
|---|---|
| Definition | small nuclear ribonucleoprotein U1 subunit 70 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | A potential mechanism underlying U1 snRNP inhibition of the cleavage step of mRNA 3' processing. | 32828285 |
| 2020-05-09 13:14:00 | Data show that two fragments in the low-complexity (LC) domain of small nuclear ribonucleoprotein U1 subunit 70 (U1-70K) can undergo liquid-liquid phase separation (LLPS). | 31723601 |
| 2020-03-21 10:07:00 | Screen using siRNA revealed depletion of U1 snRNP components SNRPA, SNRNP70 or SNRPD2 caused significant cytoplasmic localization of MEG3 reporter transcripts. | 31107149 |
| 2017-06-24 11:48:00 | These results indicate that the galectin-3-U1 snRNP-pre-mRNA ternary complex is a functional E complex and that U1 snRNP is required to assemble galectin-3 onto an active spliceosome | 27105840 |
| 2016-09-24 12:13:00 | The epitopes of U1-70K autoantibodies have been mapped at single-amino acid resolution. | 26333287 |
| Type | IDs |
|---|---|
| Synonymous | RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP |
| Gene |
UniProtKB-ID:
RU17_HUMAN,
Q9UFS1_HUMAN,
A0A024QZD5_HUMAN
UniprotKB:
P08621,
Q9UFS1,
A0A024QZD5
UniParc:
UPI000002B2E7,
UPI000000411A,
UPI000002B2E6,
UPI0000073D78,
UPI00001352E4
EMBL:
M57935,
M57934,
X84841,
AK096783,
M22636,
AL117399,
M57937,
M57939,
X06814,
M57930,
X07401,
X06817,
X06811,
CH471177,
X04654,
X07403,
AL117507,
BC000342,
M57932,
X06815,
X07402,
BC001315,
X06816,
X06812,
M57929
Ensembl:
ENSG00000104852
KO:
hsa:6625
|
| Nucleutide sequences |
EMBL-CDS:
AAA36572.1,
CAA29963.1,
CAA29960.1,
AAA36573.1,
CAA29964.1,
AAH01315.1,
CAB55969.1,
CAA29966.1,
CAA59278.1,
AAA36571.1,
CAA30303.1,
AAA03001.1,
CAA29965.1,
EAW52449.1,
BAG53365.1,
CAA28352.1,
CAA30304.1,
CAA30305.1,
CAA29961.1,
CAB55900.1,
AAH00342.1,
EAW52448.1,
EAW52446.1
Gene_ORFName:
hCG_16213
Ensembl_TRS:
ENST00000595231,
ENST00000598441,
ENST00000221448,
ENST00000401730,
ENST00000601065
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000472998,
ENSP00000471006,
ENSP00000221448,
ENSP00000468952,
ENSP00000385077
RefSeq:
XP_011525543.1,
NP_003080.2,
NP_001287998.1,
XP_011525542.2
|
| Others |
UniRef100:
UniRef100_P08621
UniRef90:
UniRef90_P08621
UniRef50:
UniRef50_P08621
UniGene:
Hs.467097
CCDS:
CCDS74417.1,
CCDS12756.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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