Type | Description |
---|---|
Definition | synuclein beta |
Date | Results | Publications |
---|---|---|
2019-08-17 10:31:00 | beta-synuclein-specific T cells were enriched in patients with chronic-progressive multiple sclerosis; findings reveal a previously unrecognized role of beta-synuclein in provoking T-cell-mediated pathology of the central nervous system | 30787438 |
2019-08-03 12:52:00 | This analyzed identify functional insertion and deletion (INDEL) variations upstream of SNCB, determined SNCB expression levels, and correlated INDEL lengths with expression levels. | 30040713 |
2019-07-20 11:02:00 | Vibrational Circular Dichroism Sheds New Light on the Competitive Effects of Crowding and beta-Synuclein on the Fibrillation Process of alpha-Synuclein. | 30239196 |
2019-07-06 12:13:00 | Results show that the non-amyloid-beta component domain of SNCB is the primary determinant of self-association leading to fibril formation, while the N- and C-terminal domains play critical roles in the fibril inhibition process. These data provide evidence that all three domains together contribute to providing effective inhibition. | 29782835 |
2019-02-09 11:59:00 | These studies could be helpful in understanding collective human synuclein behavior in various protein environments and in the modulation of the homeostasis between beta-syn and healthy versus corrupt alpha- and gamma-syn that can potentially affect PD pathology. | 29851342 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
SYUB_HUMAN,
G4Y815_HUMAN,
G4Y816_HUMAN
UniprotKB:
Q16143,
G4Y815,
G4Y816
UniParc:
UPI000003173C,
UPI0000D9B77B,
UPI00022DD57E
EMBL:
BT006627,
S69965,
JF960951,
AF053134,
JF960952,
AC091934,
JF960950,
JF960953,
BC002902,
CR457027,
AF053135,
AF053136
Ensembl:
ENSG00000074317
KO:
hsa:6620
|
Nucleutide sequences |
EMBL-CDS:
AAP35273.1,
AAH02902.1,
CAG33308.1,
AAB30860.1,
AAC80286.1,
AEQ54759.1,
AEQ54757.1,
AEQ54758.1,
AEQ54756.1
Ensembl_TRS:
ENST00000393693,
ENST00000510387,
ENST00000310112,
ENST00000506696,
ENST00000614675
|
Protein sequencees |
Ensembl_PRO:
ENSP00000422223,
ENSP00000308057,
ENSP00000377296,
ENSP00000424073,
ENSP00000479489
RefSeq:
NP_001304965.1,
NP_001350069.1,
XP_006714979.1,
NP_001304963.1,
NP_003076.1,
XP_006714977.1,
NP_001304966.1,
NP_001304964.1,
XP_011532942.1,
NP_001001502.1,
XP_006714978.1
|
Others |
UniRef100:
UniRef100_Q16143,
UniRef100_G4Y815,
UniRef100_G4Y816
UniRef90:
UniRef90_Q16143
UniRef50:
UniRef50_Q16143
UniGene:
Hs.90297
CCDS:
CCDS4406.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员