例如:"NBL1", "4681", "drought"
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6620 SNCB

6620

SNCB

synuclein beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition synuclein beta

研究结论

Date Results Publications
2019-08-17 10:31:00 beta-synuclein-specific T cells were enriched in patients with chronic-progressive multiple sclerosis; findings reveal a previously unrecognized role of beta-synuclein in provoking T-cell-mediated pathology of the central nervous system 30787438
2019-08-03 12:52:00 This analyzed identify functional insertion and deletion (INDEL) variations upstream of SNCB, determined SNCB expression levels, and correlated INDEL lengths with expression levels. 30040713
2019-07-20 11:02:00 Vibrational Circular Dichroism Sheds New Light on the Competitive Effects of Crowding and beta-Synuclein on the Fibrillation Process of alpha-Synuclein. 30239196
2019-07-06 12:13:00 Results show that the non-amyloid-beta component domain of SNCB is the primary determinant of self-association leading to fibril formation, while the N- and C-terminal domains play critical roles in the fibril inhibition process. These data provide evidence that all three domains together contribute to providing effective inhibition. 29782835
2019-02-09 11:59:00 These studies could be helpful in understanding collective human synuclein behavior in various protein environments and in the modulation of the homeostasis between beta-syn and healthy versus corrupt alpha- and gamma-syn that can potentially affect PD pathology. 29851342

名称对应

Type IDs
Gene
UniProtKB-ID: SYUB_HUMAN, G4Y815_HUMAN, G4Y816_HUMAN
UniprotKB: Q16143, G4Y815, G4Y816
UniParc: UPI000003173C, UPI0000D9B77B, UPI00022DD57E
EMBL: BT006627, S69965, JF960951, AF053134, JF960952, AC091934, JF960950, JF960953, BC002902, CR457027, AF053135, AF053136
Ensembl: ENSG00000074317
KO: hsa:6620
Nucleutide sequences
EMBL-CDS: AAP35273.1, AAH02902.1, CAG33308.1, AAB30860.1, AAC80286.1, AEQ54759.1, AEQ54757.1, AEQ54758.1, AEQ54756.1
Ensembl_TRS: ENST00000393693, ENST00000510387, ENST00000310112, ENST00000506696, ENST00000614675
Protein sequencees
Ensembl_PRO: ENSP00000422223, ENSP00000308057, ENSP00000377296, ENSP00000424073, ENSP00000479489
RefSeq: NP_001304965.1, NP_001350069.1, XP_006714979.1, NP_001304963.1, NP_003076.1, XP_006714977.1, NP_001304966.1, NP_001304964.1, XP_011532942.1, NP_001001502.1, XP_006714978.1
Others
UniRef100: UniRef100_Q16143, UniRef100_G4Y815, UniRef100_G4Y816
UniRef90: UniRef90_Q16143
UniRef50: UniRef50_Q16143
UniGene: Hs.90297
CCDS: CCDS4406.1

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