| Type | Description |
|---|---|
| Definition | BCL2 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:58:00 | Overexpression of BNIP1 suppressed proliferation, migration and invasion, and promoted apoptosis of cervical cancer cells. Silence of BNIP1 by siRNAs accelerated proliferation, migration and invasion, and inhibited apoptosis of cervical cancer cells. BNIP1 significantly inhibited mTOR, p70S6K1, and p-p70S6K1 expressions. | 30840260 |
| 2018-02-24 10:40:00 | The mitochondrial targeting domain (MTD) of Noxa has necrosis-inducing activity when conjugated with cell-penetrating peptide (CPP). In this study, we report another MTD-like motif, B1MLM, found in BNIP1, a pro-apoptotic BH3-only protein found in the endoplasmic reticulum membrane. The B1MLM peptide, conjugated with CPP, induced necrosis in a way similar to that of R8:MTD. | 29222049 |
| 2014-03-22 10:29:00 | BNip1 functions as a downstream modulator of RNF186 to direct endoplasmic reticulum stress-associated apoptotic signaling. | 23896122 |
| 2012-10-20 10:51:00 | three members of the BNIP family, BNIP1, BNIP3 and BNIP3L, are expressed in the developing brain with distinct brain region specificity | 22639046 |
| 2012-07-07 11:23:00 | ER-specific BNIP1 plays an important role in mitochondrial dynamics by modulating the mitochondrial fission protein Drp1 | 22020994 |
| Type | IDs |
|---|---|
| Synonymous | NIP1, SEC20, TRG-8 |
| Gene |
UniProtKB-ID:
SEC20_HUMAN
UniprotKB:
Q12981
UniParc:
UPI000013CA77,
UPI000000D92A,
UPI000013CA76,
UPI000013F8E3
EMBL:
U15172,
AF083957,
AF083958,
BC010959,
CH471062,
AY246554,
AF083956,
AY216799
Ensembl:
ENSG00000113734
KO:
hsa:662
|
| Nucleutide sequences |
EMBL-CDS:
AAC33124.1,
EAW61406.1,
AAC33125.1,
EAW61405.1,
EAW61412.1,
EAW61408.1,
AAO91805.1,
EAW61411.1,
AAC00020.1,
AAC33126.1,
EAW61413.1,
AAO61090.1,
EAW61410.1,
AAH10959.1,
EAW61409.1
Gene_ORFName:
TRG8
Ensembl_TRS:
ENST00000352523,
ENST00000351486,
ENST00000393770,
ENST00000231668
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377365,
ENSP00000239215,
ENSP00000239214,
ENSP00000231668
RefSeq:
NP_053583.2,
XP_011532941.1,
NP_053581.2,
XP_011532940.1,
NP_053582.2,
NP_001196.2
|
| Others |
UniRef100:
UniRef100_Q12981
UniRef90:
UniRef90_Q12981
UniRef50:
UniRef50_Q12981
UniGene:
Hs.145726
CCDS:
CCDS4386.1,
CCDS4384.1,
CCDS4385.1,
CCDS43400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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