| Type | Description |
|---|---|
| Definition | DnaJ heat shock protein family (Hsp40) member C15 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:16:00 | The mitochondrial negative regulator MCJ modulates the interplay between microbiota and the host during ulcerative colitis. | 31953445 |
| 2020-08-29 12:49:00 | Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation. | 32620763 |
| 2018-10-06 10:49:00 | In vivo treatment with an inhibitor of MCJ expression protects liver from acetaminophen-induced liver injury in mouse model at a time when N-acetylcysteine, the standard therapy, has no efficacy. Acetaminophen-induced liver injury progresses through the central participation of MCJ in vitro and in vivo. | 29233977 |
| 2013-07-27 12:26:00 | DNAJC15 localizes at the mitochondrial inner membrane, where it interacts preferentially with complex I of the electron transfer chain.DnaJC15 functions as a negative regulator of mitochondrial membrane potential and ATP production. | 23530063 |
| Type | IDs |
|---|---|
| Synonymous | 1110003P16Rik, Dnajd1 |
| Gene |
UniProtKB-ID:
DJC15_MOUSE
UniprotKB:
Q78YY6
UniParc:
UPI0000021DB2
EMBL:
BC027509,
AK002598
Ensembl:
ENSMUSG00000022013
KO:
mmu:66148
|
| Nucleutide sequences |
EMBL-CDS:
BAB22219.1,
AAH27509.1
Ensembl_TRS:
ENSMUST00000226459
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000154390
RefSeq:
NP_079660.1
|
| Others |
UniRef100:
UniRef100_Q78YY6
UniRef90:
UniRef90_Q78YY6
UniRef50:
UniRef50_Q78YY6
UniGene:
Mm.248046
CCDS:
CCDS27292.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32620763 |
Nat Commun LucÃa Barbier-Torres , Karen A Fortner , Paula Iruzubieta , Teresa C Delgado , Emily Giddings , Youdinghuan Chen , Devin Champagne , David Fernández-Ramos , Daniela Mestre , Beatriz Gomez-Santos , Marta Varela-Rey , Virginia Gutiérrez de Juan , Pablo Fernández-Tussy , Imanol Zubiete-Franco , Carmelo GarcÃa-Monzón , Ãgueda González-RodrÃguez , Dhaval Oza , Felipe Valença-Pereira , Qian Fang , Javier Crespo , Patricia Aspichueta , Frederic Tremblay , Brock C Christensen , Juan Anguita , MarÃa Luz MartÃnez-Chantar , Mercedes Rincón |
2020-07-03 | - |
| 31953445 |
Sci Rep Miguel Angel Pascual-Itoiz , Ainize Peña-Cearra , Itziar MartÃn-Ruiz , José Luis LavÃn , Carolina Simó , Héctor RodrÃguez , Estibaliz Atondo , Juana MarÃa Flores , Ana Carreras-González , Julen Tomás-Cortázar , Diego Barriales , Ainhoa Palacios , Virginia GarcÃa-Cañas , Aize Pellón , Asier Fullaondo , Ana Mª Aransay , Rafael Prados-Rosales , Rebeca MartÃn , Juan Anguita , Leticia Abecia |
2020-01-17 | - |
| 30915331 |
Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death. Front Cell Dev Biol Michael A Secinaro , Karen A Fortner , Cheryl Collins , Mercedes Rincón , Ralph C Budd |
2019-01-01 | - |
| 29233977 |
Nat Commun LucÃa Barbier-Torres , Paula Iruzubieta , David Fernández-Ramos , Teresa C Delgado , Daniel Taibo , Virginia Guitiérrez-de-Juan , Marta Varela-Rey , Mikel Azkargorta , Nicolas Navasa , Pablo Fernández-Tussy , Imanol Zubiete-Franco , Jorge Simon , Fernando Lopitz-Otsoa , Sofia Lachiondo-Ortega , Javier Crespo , Steven Masson , Misti Vanette McCain , Erica Villa , Helen Reeves , Felix Elortza , Maria Isabel Lucena , Maria Isabel Hernández-Alvarez , Antonio Zorzano , Raúl J Andrade , Shelly C Lu , José M Mato , Juan Anguita , Mercedes Rincón , MarÃa Luz MartÃnez-Chantar |
2017-12-12 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 27234056 |
Immunity Devin P Champagne , Ketki M Hatle , Karen A Fortner , Angelo D'Alessandro , Tina M Thornton , Rui Yang , Daniel Torralba , Julen Tomás-Cortázar , Yong Woong Jun , Kyo Han Ahn , Kirk C Hansen , Laura Haynes , Juan Anguita , Mercedes Rincon |
2016-06-21 | - |
| 24194600 |
Nucleic Acids Res. Gautier Koscielny , Gagarine Yaikhom , Vivek Iyer , Terrence F Meehan , Hugh Morgan , Julian Atienza-Herrero , Andrew Blake , Chao-Kung Chen , Richard Easty , Armida Di Fenza , Tanja Fiegel , Mark Grifiths , Alan Horne , Natasha A Karp , Natalja Kurbatova , Jeremy C Mason , Peter Matthews , Darren J Oakley , Asfand Qazi , Jack Regnart , Ahmad Retha , Luis A Santos , Duncan J Sneddon , Jonathan Warren , Henrik Westerberg , Robert J Wilson , David G Melvin , Damian Smedley , Steve D M Brown , Paul Flicek , William C Skarnes , Ann-Marie Mallon , Helen Parkinson |
2014-01-01 | - |
| 23530063 |
Mol. Cell. Biol. Ketki M Hatle , Phani Gummadidala , Nicolás Navasa , Edgar Bernardo , John Dodge , Brian Silverstrim , Karen Fortner , Elianne Burg , Benajamin T Suratt , Juergen Hammer , Michael Radermacher , Douglas J Taatjes , Tina Thornton , Juan Anguita , Mercedes Rincon |
2013-06-01 |
Bcl2l1,
Calr,
Gapdh,
Ndufv1,
Dnajc15
|
| 23431145 |
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc. Natl. Acad. Sci. U.S.A. Gina E Elsen , Rebecca D Hodge , Francesco Bedogni , Ray A M Daza , Branden R Nelson , Naoko Shiba , Steven L Reiner , Robert F Hevner |
2013-03-05 |
Nxph4,
Etv5,
Aldh1l1,
Lmo1,
Tshz1,
Kcnq3,
Chrna7,
Adcyap1,
Bcan,
Bcl6,
Cck,
Cckar,
Cdh11,
Cdh8,
Cdkn1c,
Crabp1,
Crym,
Dct,
Elk3,
Emx2,
Eomes,
Nr2f1,
Etv1,
Fgfr3,
Gnal,
Hey1,
Slc6a4,
Lef1,
Lhx9,
Lmo4,
Mc4r,
Mest,
Ncam2,
Nefl,
Nefm,
Nhlh2,
Nin,
Nr4a3,
Nrp2,
Pax6,
Ppp1r1b,
Stab2,
Ptpro,
Abcd4,
Robo1,
Sema5a,
Six2,
Ncor2,
Stat3,
Tbr1,
Tcf4,
Lrrtm3,
Zfp521,
Rorb,
Dner,
Tshz2,
Mmp17,
Tenm2,
Tenm3,
Spry2,
Actr3b,
Plxna4,
Map2k6,
Robo2,
Nrip1,
Fat3,
Prex1,
Dusp4,
Auts2,
Sp8,
Cdh10,
Mical2,
Htra1,
Dusp14,
Bhlhe22,
Sv2b,
Lima1,
Dnajc15,
Rgcc,
Fam210b,
Cap2,
1190002N15Rik,
Afap1,
Fgfbp3,
Rnd3,
Vit,
0610040J01Rik,
Ube2ql1,
Prdm8,
Nav2,
Cemip,
Tmem2
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员