| Type | Description |
|---|---|
| Definition | sialic acid binding Ig like lectin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. | 32223897 |
| 2021-03-06 13:29:00 | Monocyte CD169 Expression as a Biomarker in the Early Diagnosis of Coronavirus Disease 2019. | 33206973 |
| 2020-10-24 14:10:00 | Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease. | 31992280 |
| 2020-04-11 10:06:00 | circulating dendritic cell precursors, but not other blood dendritic cell subsets, are susceptible to infection by HIV-1 in a Siglec-1-dependent manner. This constitutes a unique functional feature that might represent a preferential relationship of this emerging cell type with viruses. | 31591213 |
| 2019-01-26 10:57:00 | In vitro, respiratory syncytial virus (RSV) increased expression of Siglec-1 on healthy newborn and adult monocytes. RSV-induced Siglec-1 on monocytes inhibited Interferon gamma production by adult CD4(+) T cells. In contrast,Interferon gamma production by RSV in newborns was not affected by Siglec-1. | 29266251 |
| Type | IDs |
|---|---|
| Synonymous | CD169, SIGLEC-1, SN |
| Gene |
UniProtKB-ID:
SN_HUMAN
UniprotKB:
Q9BZZ2
UniParc:
UPI000002B3EB,
UPI0000049BA6,
UPI000002B3EA
EMBL:
AK057560,
AF230073,
AK024462,
AK024459,
AK024479,
AL109804
Ensembl:
ENSG00000088827
KO:
hsa:6614
|
| Nucleutide sequences |
EMBL-CDS:
BAB15749.1,
BAB71527.1,
AAK00757.1,
BAB15769.1,
BAB15752.1
Ensembl_TRS:
ENST00000344754
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341141
RefSeq:
NP_001354018.1,
NP_075556.1
|
| Others |
UniRef100:
UniRef100_Q9BZZ2
UniRef90:
UniRef90_Q9BZZ2
UniRef50:
UniRef50_Q62230
UniGene:
Hs.31869
CCDS:
CCDS13060.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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