| Type | Description |
|---|---|
| Definition | ubiquitin-conjugating enzyme E2D 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3. | 32145025 |
| 2018-12-22 12:17:00 | Together with Riplet, Ube2D3 promotes covalent conjugation of polyubiquitin chains to RIG-I, while Ube2N preferentially facilitates production of unanchored chains. In the presence of these chains, RIG-I induces MAVS aggregation directly on the mitochondria. Data thus reveal two essential mechanisms underlying the activation of RIG-I and MAVS for triggering innate immune signaling in response to viral infection in cells. | 28469175 |
| Type | IDs |
|---|---|
| Synonymous | 1100001F19Rik, 9430029A22Rik, AA414951 |
| Gene |
UniProtKB-ID:
UB2D3_MOUSE,
Q4QQL2_MOUSE
UniprotKB:
P61079,
Q4QQL2
UniParc:
UPI000000004D
EMBL:
AK167801,
AK032885,
AK153111,
AK167077,
AK004001,
AK151295,
AK169177,
BC098220,
AK167138,
BC057941,
AK159546,
AK088448,
AK165235,
AK049906,
AK152541,
AK159125,
AK159963,
AK151594,
AK167650,
AK077666,
AK153100
Ensembl:
ENSMUSG00000078578
KO:
mmu:66105
|
| Nucleutide sequences |
EMBL-CDS:
BAC33981.1,
BAB23116.1,
BAC40357.1,
BAC36940.1,
AAH57941.1,
BAC28070.1,
BAE31728.1,
BAE39701.1,
BAE30534.1,
BAE35172.1,
BAE35518.1,
BAE39283.1,
BAE38093.1,
BAE40955.1,
BAE31721.1,
BAE34839.1,
BAE30279.1,
BAE39237.1,
BAE39829.1,
BAE31296.1,
AAH98220.1
Ensembl_TRS:
ENSMUST00000197539,
ENSMUST00000199613,
ENSMUST00000166033,
ENSMUST00000197859,
ENSMUST00000106291,
ENSMUST00000196446
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000143608,
ENSMUSP00000143301,
ENSMUSP00000143065,
ENSMUSP00000101898,
ENSMUSP00000130096,
ENSMUSP00000142974
RefSeq:
XP_036019113.1,
NP_001343525.1,
NP_001343523.1,
NP_001343526.1,
NP_079632.1,
XP_036019110.1,
XP_036019111.1,
NP_001343527.1,
XP_036019112.1,
NP_001343524.1,
XP_036019109.1
|
| Others |
UniRef100:
UniRef100_P61077
UniRef90:
UniRef90_P61077
UniRef50:
UniRef50_P61077
UniGene:
Mm.49884,
Mm.391601,
Mm.471976
CCDS:
CCDS38644.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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