| Type | Description |
|---|---|
| Definition | sphingomyelin phosphodiesterase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 12:24:00 | Low NSMase1 expression is associated with hepatocellular carcinoma. | 30106227 |
| 2015-10-03 11:31:00 | Interestingly, neutral but not acid sphingomyelinase was mandatory for PorBIA -mediated Neisseria gonorrhoeae invasion into host cells. | 25224994 |
| 2015-08-08 10:49:00 | nSMase1 (sphingomyelin phosphodiesterase 2, SMPD2)has a common central role in ceramide signaling during the stress and cytokine responses and apoptosis. | 25168245 |
| 2014-10-04 10:58:00 | These data suggest that Ox-LDL activates N-SMase-ceramide signaling pathway, and stimulates phosphorylation of p38 MAPK, leading to apoptosis in vascular smooth muscle cells, which initiates VSMC calcification. | 24358176 |
| 2013-03-09 12:15:00 | NSM2 plays a key role in the cellular response to hyperosmolar stress, and its activity regulates both cytokine secretion and lipid droplet formation. | 22899568 |
| Type | IDs |
|---|---|
| Synonymous | ISC1, NSMASE, NSMASE1 |
| Gene |
UniProtKB-ID:
NSMA_HUMAN
UniprotKB:
O60906
UniParc:
UPI000013CFAC
EMBL:
AL109947,
BC000038,
AJ222801
Ensembl:
ENSG00000135587
KO:
hsa:6610
|
| Nucleutide sequences |
EMBL-CDS:
CAA10995.1,
AAH00038.1
Ensembl_TRS:
ENST00000258052
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258052
RefSeq:
NP_003071.2,
XP_011534381.1,
XP_005267166.1,
XP_024302295.1,
XP_024302294.1
|
| Others |
UniRef100:
UniRef100_O60906
UniRef90:
UniRef90_O60906
UniRef50:
UniRef50_O60906
UniGene:
Hs.55235
CCDS:
CCDS5075.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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