| Type | Description |
|---|---|
| Definition | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 12:27:00 | Data show that both CEBPE and SMARCD2 loss-of-function mutations identified in patients with neutrophil-specific granule deficiency abolish the interaction with SWI/SNF and secondary granule gene expression, thus providing a molecular basis for this disease. | 28369034 |
| 2017-09-23 12:27:00 | Defective expression of SMARCD2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2) leads to transcriptional and chromatin changes in acute myeloid leukemia (AML) promyelocytic cells, suggesting SMARCD2 is a key factor controlling myelopoiesis and is a potential tumor suppressor in leukemia. | 28369036 |
| 2016-06-28 10:57:00 | the role of SMARCA4 and the two SWI/SNF subunits SMARCD2/BAF60B and DPF2/BAF45D in leukaemia, was investigated. | 26571505 |
| 2010-04-19 11:22:00 | the Rac- and Unkempt-dependent process leading to BAF60b ubiquitination takes place in the nuclear compartment | 20148946 |
| Type | IDs |
|---|---|
| Synonymous | BAF60B, CRACD2, PRO2451, Rsc6p, SGD2 |
| Gene |
UniProtKB-ID:
SMRD2_HUMAN,
J3KMX2_HUMAN
UniprotKB:
Q92925,
J3KMX2
UniParc:
UPI00017A874A,
UPI00002011F0,
UPI0000D695F8,
UPI0001F4E028
EMBL:
BC018953,
AC015651,
AF113019,
AK300939,
U66618,
BC142963,
CH471109,
AK303951
Ensembl:
ENSG00000108604
KO:
hsa:6603
|
| Nucleutide sequences |
EMBL-CDS:
AAI42964.1,
BAG64878.1,
BAG62568.1,
AAH18953.2,
EAW94267.1,
AAF20280.1,
AAC50696.1
Gene_ORFName:
PRO2451
Ensembl_TRS:
ENST00000448276,
ENST00000323347,
ENST00000225742
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318451,
ENSP00000392617,
ENSP00000225742
RefSeq:
NP_001317369.1,
NP_001317368.1,
NP_001091896.1
|
| Others |
UniRef100:
UniRef100_Q92925
UniRef90:
UniRef90_Q92925
UniRef50:
UniRef50_Q92925
UniGene:
Hs.250581
CCDS:
CCDS45756.1,
CCDS82188.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员