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66016 Kcnmb4

66016

Kcnmb4

potassium calcium-activated channel subfamily M regulatory beta subunit 4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition potassium calcium-activated channel subfamily M regulatory beta subunit 4

研究结论

Date Results Publications
2021-02-06 13:57:00 Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors. 32070382
2015-07-25 11:30:00 The results demonstrate a modification in the mitochondrial BKCa channel gating properties in membrane preparations coming from a streptozotocin model of diabetic rats, an effect potentially linked to a change in BKCa beta4 and alpha subunits expression. 25344764
2014-11-08 13:13:00 Study shows that beta4 subunit of the MaxiK channel has no potential endocytic signal and 2 specific amino acids in the functional basic motif retention/retrieval trafficking signal at the C-terminus may play a role in controlling cellular excitability 24486049
2012-03-31 11:50:00 BKbeta4 expression in astrocytes likely participates in regulating astrocytic voltage gradients and maintaining poassium homeostasis, hence enabling astrocytes to fulfill their complex regulatory influence on proper brain function. 21438011
2012-01-28 10:58:00 These results suggest that fast-gating, type I BK channels lacking beta4 can increase neuronal excitability in response to reduced phosphatase activity and activation of calcium channels. 21848922

名称对应

Type IDs
Gene
UniProtKB-ID: KCMB4_RAT, B1WBP1_RAT
UniprotKB: Q9ESK8, B1WBP1
UniParc: UPI00000E5F3F
EMBL: BC161829, CH473960, AY028605, AB050637
Ensembl: ENSRNOG00000054458
KO: rno:66016
Nucleutide sequences
EMBL-CDS: BAB17595.1, AAK21964.1, AAI61829.1, EDM16670.1
Gene_ORFName: rCG_48867
Ensembl_TRS: ENSRNOT00000085579
Protein sequencees
Ensembl_PRO: ENSRNOP00000075448
RefSeq: NP_076450.1
Others
UniRef100: UniRef100_Q9ESK8
UniRef90: UniRef90_Q9JIN6
UniRef50: UniRef50_Q9JIN6
UniGene: Rn.162953

全选

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研究热度

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