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65986 ZBTB10

65986

ZBTB10

zinc finger and BTB domain containing 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger and BTB domain containing 10

研究结论

Date Results Publications
2019-08-31 12:20:00 ZBTB10 co-localizes with a subset of telomeres in ALT-positive U2OS cells and interacts with TRF2/RAP1 via the N-terminal region of TRF2. Our data establishes ZBTB10 as a novel variant repeat binding protein at ALT telomeres. 30629181
2014-05-17 13:50:00 Sp1, Sp3, and Sp4 and Sp-regulated genes were downregulated by curcuminoids in SW-480 and this was accompanied by suppression of microRNA-27a (miR-27a) and induction of ZBTB10, an mRNA target of miR-27a and a transcriptional repressor of Sp expression. 23471840
2014-01-11 10:29:00 Collectively, these results indicated that stimulation of ovarian cancer cell VEGF, Cox2 and survivin expression by FSH involves the microRNA27a: ZBTB10-specificity protein pathway. 23254909
2010-07-05 11:42:00 Study show that miR-27a indirectly regulates E2-responsiveness in MCF-7 cells through suppression of ZBTB10, thereby enhancing expression of ERalpha. 20382698

名称对应

Type IDs
Synonymous RINZF
Gene
UniProtKB-ID: ZBT10_HUMAN, Q9H9H3_HUMAN
UniprotKB: Q96DT7, Q9H9H3
UniParc: UPI0000E5AEF3, UPI000006D39D, UPI00015D57D9, UPI000006E576, UPI0000F57A7E
EMBL: BC050061, AJ319673, AC009812, AK056913, BC127098, AK022814, AJ507398
Ensembl: ENSG00000205189
KO: hsa:65986
Nucleutide sequences
EMBL-CDS: CAD45447.1, AAH50061.1, BAB71309.1, CAC40989.1, AAI27099.1, BAB14256.1
Ensembl_TRS: ENST00000610895, ENST00000455036, ENST00000379091, ENST00000426744, ENST00000430430
Protein sequencees
Ensembl_PRO: ENSP00000368384, ENSP00000387462, ENSP00000416134, ENSP00000484716, ENSP00000412036
RefSeq: NP_076418.3, NP_001264074.1, NP_001099009.1
Others
UniRef100: UniRef100_Q9H9H3, UniRef100_Q96DT7
UniRef90: UniRef90_Q9H9H3, UniRef90_Q96DT7
UniRef50: UniRef50_Q96DT7, UniRef50_G1KUW9
UniGene: Hs.591868
CCDS: CCDS64920.1, CCDS47880.1

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