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65969 Cubn

65969

Cubn

cubilin (intrinsic factor-cobalamin receptor)

protein-coding

Mus musculus

基因描述

Type Description
Definition cubilin (intrinsic factor-cobalamin receptor)

研究结论

Date Results Publications
2020-07-18 12:04:00 In the proximal kidney tubules cubilin binding to albumin is tuned to capture normally filtered levels of the protein. 32200668
2019-09-14 11:01:00 Low cubilin expression is associated with proteinuria. 29186471
2018-02-17 10:17:00 Cubilin is involved in 25(OH) vitamin D uptake by adipocytes. 29186386
2016-12-31 11:49:00 In adult mouse testes, strong Cubn immunoreactivity was found in the elongating spermatids. In Sertoli cells and peritubular cells, Cubn immunoreactivity was weak throughout the testis development. In the inter-stitium, Cubn immunoreactivity was found in foetal Leydig cells, was weak to negligible in the stem cells and progenitor Leydig cells and was strong in immature and adult Leydig cells. 26148765
2014-08-30 11:17:00 Cubilin deficiency reduces renal salvage and delivery back to the blood of albumin and apolipoprotein (apo)A-I, which decreases blood levels of albumin and apoA-I/HD 24357674

名称对应

Type IDs
Synonymous AA408369, AL022750, D2Wsu88e
Gene
UniProtKB-ID: CUBN_MOUSE
UniprotKB: Q9JLB4
UniParc: UPI0000603846
EMBL: AL928807, AF197159, AL773538
Ensembl: ENSMUSG00000026726
KO: mmu:65969
Nucleutide sequences
EMBL-CDS: AAF61487.1
Ensembl_TRS: ENSMUST00000091436
Protein sequencees
Ensembl_PRO: ENSMUSP00000089009
RefSeq: NP_001074553.1
Others
UniRef100: UniRef100_Q9JLB4
UniRef90: UniRef90_Q9JLB4
UniRef50: UniRef50_O60494
UniGene: Mm.313915
CCDS: CCDS38048.1

全选

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研究热度

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