| Type | Description |
|---|---|
| Definition | calsyntenin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | Amyloidogenic processing of amyloid beta protein precursor (APP) is enhanced in the brains of alcadein alpha-deficient mice. | 32467230 |
| 2015-04-25 10:25:00 | These results indicate that regulated intramembrane proteolysis of Alca by gamma-secretase regulates APP trafficking and the production of Abeta in vivo. | 25406318 |
| 2014-08-23 12:15:00 | these results highlight a key role for calsyntenin-1 in the transport of NMDA receptors to synaptic targets, which is necessary for the maturation of neuronal circuits during early development. | 24966372 |
| 2013-02-16 11:34:00 | Alcalpha is efficiently processed in part to minimize the inappropriate peripheral retention of kinesin-1 | 22905201 |
| 2012-11-24 10:18:00 | Immunoisolated calsyntenin-1 organelles from murine brain homogenates; determined their proteome by MS. Found calsyntenin-1 organelles are endowed with components of the endosomal trafficking machinery and contained the beta-amyloid precursor protein (APP). | 20925061 |
| Type | IDs |
|---|---|
| Synonymous | 1810034E21Rik, Cst-1, Cstn1 |
| Gene |
UniProtKB-ID:
CSTN1_MOUSE
UniprotKB:
Q9EPL2
UniParc:
UPI00001936D1,
UPI00000272F4
EMBL:
BC029027,
CU210912,
BC053843,
CU207384,
AL607078,
AJ289016,
AK173059
Ensembl:
ENSMUSG00000039953
KO:
mmu:65945
|
| Nucleutide sequences |
EMBL-CDS:
BAD32337.1,
AAH29027.1,
CAC17788.1,
AAH53843.1
Ensembl_TRS:
ENSMUST00000039144,
ENSMUST00000105691
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036962,
ENSMUSP00000101316
RefSeq:
NP_075538.1,
XP_006539157.1,
XP_030109553.1,
XP_036020188.1,
NP_001277918.1,
XP_006539156.1,
XP_030109552.1
|
| Others |
UniRef100:
UniRef100_Q9EPL2
UniRef90:
UniRef90_Q9EPL2
UniRef50:
UniRef50_Q9EPL2
UniGene:
Mm.38993
CCDS:
CCDS18963.1,
CCDS71522.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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