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6585 SLIT1

6585

SLIT1

slit guidance ligand 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition slit guidance ligand 1

研究结论

Date Results Publications
2020-06-06 10:19:00 SLIT1-mutated hematopoietic stem cells have a role in clonal hematopoiesis in acquired aplastic anemia 31186493
2019-05-18 12:17:00 Findings show that SLIT1 is a direct target of SUV39H2 which binds to its promoter and catalyzes H3K9 tri-methylation to silence SLIT1 expression. 29458143
2010-01-21 00:00:00 Slits are negative regulators of Sdf1 and Cxcr4 in breast cancer cells. 18829537
2010-01-21 00:00:00 evidence showing that Slit1 and Slit2 proteins are selective inhibitors and repellents for dorsally projecting, but not for ventrally projecting, cranial motor axons 16162649
2010-01-21 00:00:00 heparin/HS is an integral component of the minimal Slit-Robo signaling complex and serves to stabilize the relatively weak Slit-Robo interaction 17062560

名称对应

Type IDs
Synonymous MEGF4, SLIL1, SLIT-1, SLIT3
Gene
UniProtKB-ID: SLIT1_HUMAN, A6H8V1_HUMAN
UniprotKB: O75093, A6H8V1
UniParc: UPI00001F9491, UPI000025232E, UPI0000D45F5C
EMBL: AB011537, AL512424, BC146851, CH471066, BC146761, AB017167, AY029183, AL442123
Ensembl: ENSG00000187122
KO: hsa:6585
Nucleutide sequences
EMBL-CDS: AAK31796.1, BAA32465.3, AAI46852.1, BAA35184.1, EAW49958.1, AAI46762.1
Ensembl_TRS: ENST00000266058
Protein sequencees
Ensembl_PRO: ENSP00000266058
RefSeq: NP_003052.2
Others
UniRef100: UniRef100_O75093, UniRef100_A6H8V1
UniRef90: UniRef90_O75093
UniRef50: UniRef50_O75093
UniGene: Hs.632082
CCDS: CCDS7453.1

全选

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研究热度

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