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6581 SLC22A3

6581

SLC22A3

solute carrier family 22 member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 22 member 3

研究结论

Date Results Publications
2020-11-21 13:23:00 Protein expression of ABCC2 and SLC22A3 associates with prognosis of pancreatic adenocarcinoma. 31874997
2020-07-18 11:30:00 The cytoplasmic dsRNA increased OCT3 mRNA, cytoplasmic dsDNAs, such as salmon sperm DNA and poly(dA:dT), did not. Interestingly, the expression of NANOG, SOX2, Kruppel-like factor 4 (KLF4), and proto-oncogene c-Myc was also increased by cytoplasmic dsRNA. 31615841
2020-02-08 11:53:00 Heterologous PITX2 expression induced ABCB1, repressed hOCT3/SLC22A3, enhanced vincristine resistance and diminished proliferation inhibition in colonic and kidney tumor cells. 30742940
2019-11-23 11:41:00 Data suggest that an organic cation transporter 3 (OCT3) promoter haplotype affects the pharmacokinetics of metformin in Koreans as well as the OCT3 transcription rate. 30446679
2019-11-02 12:49:00 Expression of SLC22A3 was significantly higher in colorectal cancer tissues than that in paired normal tissues. The phenotypes of proliferation, migration, invasion, cell cycle and apoptosis of colorectal cancer cell were significantly affected by SLC22A3 in vitro. Results revealed a novel susceptible locus, rs420038 in SLC22A3, which may be involved in colorectal cancer development and progression. 30561001

名称对应

Type IDs
Synonymous EMT, EMTH, OCT3
Gene
UniProtKB-ID: S22A3_HUMAN
UniprotKB: O75751
UniParc: UPI0000130BB7
EMBL: AJ001417, AL591069, CH471051, AL355506, AK314590, AF078749
Ensembl: ENSG00000146477
KO: hsa:6581
Nucleutide sequences
EMBL-CDS: AAD20977.1, CAA04751.1, EAW47599.1, BAG37164.1
Ensembl_TRS: ENST00000275300
Protein sequencees
Ensembl_PRO: ENSP00000275300
RefSeq: XP_005267163.1, XP_016866692.1, XP_011534377.1, XP_011534378.1, NP_068812.1, XP_005267164.1
Others
UniRef100: UniRef100_O75751
UniRef90: UniRef90_O75751
UniRef50: UniRef50_O75751
UniGene: Hs.567337
CCDS: CCDS5277.1

全选

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