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6576 SLC25A1

6576

SLC25A1

solute carrier family 25 member 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 25 member 1

研究结论

Date Results Publications
2021-02-20 13:33:00 Mitochondrial SLC25 Carriers: Novel Targets for Cancer Therapy. 32455902
2019-09-21 12:18:00 SLC25A1 plays a key role in maintaining the mitochondrial pool of citrate and redox balance in cancer stem cells (CSCs), whereas its inhibition leads to reactive oxygen species build-up thereby inhibiting the self-renewal capability of CSCs. 29651165
2019-06-15 10:36:00 High expression of mitochondrial citrate transporter was associated with invasion and advanced tumor stage across many human cancers. 29510993
2019-03-09 11:37:00 SLC25A1 mutations might be associated with mitochondrial complex V deficiency and should be considered in the differential diagnosis of mitochondrial respiratory chain defects. 29226520
2018-12-22 10:19:00 SLC25A1 and ACLY upregulation suggests that metabolic reprogramming in Behcet's syndrome involves the citrate pathway dysregulation. 30050389

名称对应

Type IDs
Synonymous CMS23, CTP, D2L2AD, SEA, SLC20A3
Gene
UniProtKB-ID: TXTP_HUMAN, D9HTE9_HUMAN, B4DP62_HUMAN
UniprotKB: P53007, D9HTE9, B4DP62
UniParc: UPI0000EE7C56, UPI0000137851, UPI0001DAF60C
EMBL: U25147, L76134, AK292313, CH471176, AC004463, BC008061, BC004980, AK298204, L75823, HM037273
Ensembl: ENSG00000100075
KO: hsa:6576
Nucleutide sequences
EMBL-CDS: AAH04980.1, BAF85002.1, AAH08061.1, AAL40090.1, AAL40091.1, AAB08515.1, ADI78884.1, EAX03050.1, EAX03051.1, EAX03049.1, BAG60474.1
Gene_ORFName: hCG_17246
Ensembl_TRS: ENST00000215882, ENST00000451283
Protein sequencees
Ensembl_PRO: ENSP00000215882, ENSP00000401480
RefSeq: NP_005975.1, NP_001274316.1, NP_001243463.1
Others
UniRef100: UniRef100_P53007, UniRef100_D9HTE9
UniRef90: UniRef90_A0A2K5SIC9, UniRef90_P53007
UniRef50: UniRef50_H9G6D8, UniRef50_P53007
UniGene: Hs.111024
CCDS: CCDS13758.1

全选

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