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6570 SLC18A1

6570

SLC18A1

solute carrier family 18 member A1

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 18 member A1

研究结论

Date Results Publications
2020-02-01 13:34:00 Finding suggests that monoamine uptake by VMAT1 initially declined in early human evolution (from 130Glu/136Asn to 130Gly/136Thr) but increased along with the emergence of the 130Gly/136Ile variant around the time of the out of Africa dispersal of modern humans. 31791232
2020-01-25 14:25:00 SV2 was highly expressed in neuroblastoma (NB) and can thus be useful marker in NB diagnostics. VMAT1 and VMAT2 were also expressed in NB but similar to syn less reliable as tumor markers. 31317476
2019-08-17 12:23:00 SLC18A1 variants correlated with Anger and Vigor scores, only among males. 30656852
2019-05-04 12:42:00 SLC18A1 as one potential pleiotropic gene overlapped between Mood disorders and Cardiometabolic diseases. Genetic variation in SLC18A1 made statistically significant contributions to Body Mass Index. 29998543
2018-12-01 10:05:00 SLC18A1 might complement other biomarkers currently under study in relation to programmed cell death protein 1/programmed cell death protein ligand 1 inhibition 30194079

名称对应

Type IDs
Synonymous CGAT, VAT1, VMAT1
Gene
UniProtKB-ID: VMAT1_HUMAN, Q96GL6_HUMAN
UniprotKB: P54219, Q96GL6
UniParc: UPI00001389CE, UPI000186C999, UPI000006FF6B, UPI000013D686
EMBL: AC025853, BC009387, U39905, BC006317
Ensembl: ENSG00000036565
KO: hsa:6570
Nucleutide sequences
EMBL-CDS: AAH06317.1, AAC50472.1, AAH09387.1
Ensembl_TRS: ENST00000265808, ENST00000381608, ENST00000440926, ENST00000519026, ENST00000276373, ENST00000437980, ENST00000517776
Protein sequencees
Ensembl_PRO: ENSP00000265808, ENSP00000429664, ENSP00000276373, ENSP00000413361, ENSP00000387549, ENSP00000371021, ENSP00000428001
RefSeq: NP_001135797.1, XP_011542927.1, NP_003044.1, NP_001129163.1, NP_001135796.1, XP_011542928.1
Others
UniRef100: UniRef100_P54219, UniRef100_Q96GL6
UniRef90: UniRef90_P54219, UniRef90_Q96GL6
UniRef50: UniRef50_P54219, UniRef50_A0A3Q3BG18
UniGene: Hs.158322
CCDS: CCDS6013.1, CCDS47814.1, CCDS47815.1

全选

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