| Type | Description |
|---|---|
| Definition | solute carrier family 12 member 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:14:00 | The main goal of the review is to discuss the molecular features and tissue-specific functions of KCC1 from the hematological perspective for the greater part. As will be seen, the characterization of KCC1 has led the way to important findings and promising therapeutic avenues. [review] | 31296230 |
| 2018-11-24 10:47:00 | data indicate that Zn(2+) acting via ZnR/GPR39 has a direct role in controlling Cl(-) absorption via upregulation of basolateral KCC1 in the colon. Moreover, colonocytic ZnR/GPR39 and KCC1 reduce water loss during diarrhea and may therefore serve as effective drug targets. | 28093242 |
| 2012-01-07 10:47:00 | The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1/2 and NCC were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions. | 21613606 |
| 2011-12-10 11:19:00 | Insulin-like growth factors I can induce the upregulation of KCC1 gene, and KCC1 gene participates in the invasion ability of HEC-1B cells through the ERK signaling pathway. | 21666489 |
| 2011-10-29 10:21:00 | KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity | 21733850 |
| Type | IDs |
|---|---|
| Synonymous | CTC-479C5.17, KCC1, hKCC1 |
| Gene |
UniProtKB-ID:
S12A4_HUMAN,
B4DF30_HUMAN
UniprotKB:
Q9UP95,
B4DF30
UniParc:
UPI000002B30A,
UPI000002B30B,
UPI00019863A9,
UPI00019863A8,
UPI00017A6FDC,
UPI00019863AA,
UPI0000135421,
UPI000002B30C
EMBL:
AK316415,
U55054,
AF053402,
AF054505,
AK299042,
AY026038,
AC040162,
AK293906,
AF047338,
AK302790,
BC021193,
AK293956,
AF054506
Ensembl:
ENSG00000124067
KO:
hsa:6560
|
| Nucleutide sequences |
EMBL-CDS:
AAK01946.1,
BAG57330.1,
AAC32815.1,
BAH14786.1,
AAC35282.1,
AAC50563.1,
BAG61116.1,
AAH21193.1,
AAC39684.1,
BAG63994.1,
AAC39685.1,
BAG57291.1
Ensembl_TRS:
ENST00000576616,
ENST00000541864,
ENST00000537830,
ENST00000422611,
ENST00000316341
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445962,
ENSP00000318557,
ENSP00000438334,
ENSP00000395983,
ENSP00000458902
RefSeq:
NP_001139434.1,
NP_001139435.1,
NP_005063.1,
NP_001139433.1,
NP_001139436.1
|
| Others |
UniRef100:
UniRef100_Q9UP95,
UniRef100_B4DF30
UniRef90:
UniRef90_Q9UP95
UniRef50:
UniRef50_Q9UP95
UniGene:
Hs.10094
CCDS:
CCDS54031.1,
CCDS10855.1,
CCDS54032.1,
CCDS54030.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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