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6555 SLC10A2

6555

SLC10A2

solute carrier family 10 member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 10 member 2

研究结论

Date Results Publications
2021-04-17 13:14:00 S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. 33189717
2021-01-16 15:58:00 Efficient SNP editing in haploid human pluripotent stem cells. 32162131
2021-01-02 12:49:00 S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells. 32071081
2020-07-18 10:49:00 Results found that, in obesity, intestinal bile acid absorption is increased secondary to increased expression of apical bile acid cotransporter, ASBT, in the brush border membrane of villus cells. The mechanism of stimulation of ASBT expression is likely secondary to increased expression of FXR in these cells. 31623375
2020-06-27 10:51:00 Study data confirms that tyrosine phosphorylation mediated by Src family kinases (SFKs), in particular, regulates surface expression, function, and stability of hASBT. 31194565

名称对应

Type IDs
Synonymous ASBT, IBAT, ISBT, NTCP2, PBAM
Gene
UniProtKB-ID: NTCP2_HUMAN
UniprotKB: Q12908
UniParc: UPI000013CB9B
EMBL: U67673, U67669, BC130521, U67672, Z54350, U10417, AE014294, CH471085, U67670, AL161771, U67674, BC130523, U67671
Ensembl: ENSG00000125255
KO: hsa:6555
Nucleutide sequences
EMBL-CDS: AAI30524.1, EAX09074.1, AAI30522.1, CAA91161.1, AAN16026.1, AAC95398.1, AAC51870.1
Ensembl_TRS: ENST00000245312
Protein sequencees
Ensembl_PRO: ENSP00000245312
RefSeq: NP_000443.2
Others
UniRef100: UniRef100_Q12908
UniRef90: UniRef90_Q12908
UniRef50: UniRef50_Q12908
UniGene: Hs.194783
CCDS: CCDS9506.1

全选

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研究热度

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