| Type | Description |
|---|---|
| Definition | solute carrier family 9 member A1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia. | 32703317 |
| 2020-07-25 12:12:00 | our results suggest that dysregulation of NHE1 contributes to breaches in blood brain barrier integrity, drug penetrance, and the behavioral sensitivity to the antimigraine agent, sumatriptan. | 32469979 |
| 2020-06-27 11:50:00 | Findings imply that Na/H exchanger 1 (NHE1) is a potential target in cytotoxic or differentiation-induction treatment for acute myeloid leukemia (AML). | 31561854 |
| 2020-06-27 11:26:00 | NHE1 overexpression specifically induces death of induced pluripotent stem cells via sustained ROCK activation, probably caused by an increase in local pH near NHE1 | 31723030 |
| 2020-01-11 10:47:00 | By measuring the kinetic parameters of the NHE1 activity in the oncogene-transformed cells, it was found that NHE1 was constitutively activated by the oncogene expression via an increased sensitivity of its allosteric proton regulatory sites for the intracellular H+. This (the lowering of the H+-sensitivity threshold of NHE1) was responsible for its constitutive activation and the subsequent extracellular acidification | 31357694 |
| Type | IDs |
|---|---|
| Synonymous | APNH, LIKNS, NHE-1, NHE1, PPP1R143 |
| Gene |
UniProtKB-ID:
SL9A1_HUMAN,
B2RAH2_HUMAN
UniprotKB:
P19634,
B2RAH2
UniParc:
UPI000175072A,
UPI000006E750,
UPI000012FD1B
EMBL:
AF141351,
AF141356,
AF146439,
AL590640,
AF146437,
AF146433,
AF141354,
CH471059,
AF141355,
AF141357,
S68616,
AF141358,
AK314190,
M81768,
AF146431,
AL137860,
AF141353,
AF146436,
AF141359,
AF146432,
AF146430,
AF146438,
AF141352,
AF146434,
AF146435,
AF141350,
BC012121
Ensembl:
ENSG00000090020
KO:
hsa:6548
|
| Nucleutide sequences |
EMBL-CDS:
AAF21358.1,
AAF21353.1,
AAF25601.1,
AAF21355.1,
AAF25592.1,
AAC60606.1,
EAX07773.1,
AAH12121.1,
AAF21352.1,
AAF21356.1,
AAF21354.1,
AAF25594.1,
AAB59460.1,
AAF25595.1,
AAF21357.1,
AAF21351.1,
AAF21359.1,
AAF25596.1,
AAF25593.1,
AAF25600.1,
AAF21350.1,
AAF25597.1,
AAF25598.1,
AAF25599.1,
EAX07774.1,
BAG36869.1
Ensembl_TRS:
ENST00000263980,
ENST00000374086
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363199,
ENSP00000263980
RefSeq:
NP_003038.2,
XP_011540323.1
|
| Others |
UniRef100:
UniRef100_P19634,
UniRef100_B2RAH2
UniRef90:
UniRef90_P19634
UniRef50:
UniRef50_P19634
UniGene:
Hs.91389,
Hs.469116
CCDS:
CCDS295.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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