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653361 NCF1

653361

NCF1

neutrophil cytosolic factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition neutrophil cytosolic factor 1

研究结论

Date Results Publications
2020-11-21 13:19:00 Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population. 31705128
2020-09-26 13:03:00 P-Tyr42 RhoA GTPase amplifies superoxide formation through p47phox, phosphorylated by ROCK. 31973815
2020-06-27 12:14:00 Data showed that proliferating cell nuclear antigen (PCNA) associated with neutrophil cytosolic factor 1 (p47phox), a key subunit of NADPH oxidase in neutrophils and that this association regulated reactive oxygen species production. 31492810
2020-04-25 12:43:00 Polymorphism NCF1-339, rs201802880 mediated decreased NADPH oxidase function, is associated with high interferon activity and impaired formation of neutrophil extracellular traps in systemic lupus erythematosus, allowing dependence on mitochondrial reactive oxygen species Also a striking connection between the deficient NCF1-339 genotypes and the presence of phospholipid antibodies and antiphospholipid syndrome 31704719
2020-01-11 10:34:00 flow cytometry for p47(phox) expression quickly identifies patients and carriers of p47(phox) CGD, and genomic ddPCR identifies patients and carriers of DeltaGT NCF1, the most common mutation in p47(phox) CGD. 30651282

名称对应

Type IDs
Synonymous NCF1A, NOXO2, SH3PXD1A, p47phox
Gene
UniProtKB-ID: NCF1_HUMAN
UniprotKB: P14598
UniParc: UPI000150D9DC, UPI000013E46E
EMBL: AK127905, M25665, AF330627, AK223217, AH005796, AC124781, AF330626, U25793, AK292094, AC004883, BC065731, AF184614, DQ314878, AC083884, AF330625, BC002816, M55067
Ensembl: ENSG00000158517
KO: hsa:653361
Nucleutide sequences
EMBL-CDS: ABC40737.1, BAG54596.1, AAK19516.1, AAH02816.1, BAF84783.1, AAS07465.1, AAA93232.1, AAF34737.1, BAD96937.1, AAA59901.1, AAK19517.1, AAA57209.1, AAK19518.1, AAB95193.1, AAH65731.1
Ensembl_TRS: ENST00000289473
Protein sequencees
Ensembl_PRO: ENSP00000289473
RefSeq: NP_000256.4
Others
UniRef100: UniRef100_P14598
UniRef90: UniRef90_P14598
UniRef50: UniRef50_P14598
UniGene: Hs.647047, Hs.655201
CCDS: CCDS34657.1

全选

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