Type | Description |
---|---|
Definition | neutrophil cytosolic factor 1 |
Date | Results | Publications |
---|---|---|
2020-11-21 13:19:00 | Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population. | 31705128 |
2020-09-26 13:03:00 | P-Tyr42 RhoA GTPase amplifies superoxide formation through p47phox, phosphorylated by ROCK. | 31973815 |
2020-06-27 12:14:00 | Data showed that proliferating cell nuclear antigen (PCNA) associated with neutrophil cytosolic factor 1 (p47phox), a key subunit of NADPH oxidase in neutrophils and that this association regulated reactive oxygen species production. | 31492810 |
2020-04-25 12:43:00 | Polymorphism NCF1-339, rs201802880 mediated decreased NADPH oxidase function, is associated with high interferon activity and impaired formation of neutrophil extracellular traps in systemic lupus erythematosus, allowing dependence on mitochondrial reactive oxygen species Also a striking connection between the deficient NCF1-339 genotypes and the presence of phospholipid antibodies and antiphospholipid syndrome | 31704719 |
2020-01-11 10:34:00 | flow cytometry for p47(phox) expression quickly identifies patients and carriers of p47(phox) CGD, and genomic ddPCR identifies patients and carriers of DeltaGT NCF1, the most common mutation in p47(phox) CGD. | 30651282 |
Type | IDs |
---|---|
Synonymous | NCF1A, NOXO2, SH3PXD1A, p47phox |
Gene |
UniProtKB-ID:
NCF1_HUMAN
UniprotKB:
P14598
UniParc:
UPI000150D9DC,
UPI000013E46E
EMBL:
AK127905,
M25665,
AF330627,
AK223217,
AH005796,
AC124781,
AF330626,
U25793,
AK292094,
AC004883,
BC065731,
AF184614,
DQ314878,
AC083884,
AF330625,
BC002816,
M55067
Ensembl:
ENSG00000158517
KO:
hsa:653361
|
Nucleutide sequences |
EMBL-CDS:
ABC40737.1,
BAG54596.1,
AAK19516.1,
AAH02816.1,
BAF84783.1,
AAS07465.1,
AAA93232.1,
AAF34737.1,
BAD96937.1,
AAA59901.1,
AAK19517.1,
AAA57209.1,
AAK19518.1,
AAB95193.1,
AAH65731.1
Ensembl_TRS:
ENST00000289473
|
Protein sequencees |
Ensembl_PRO:
ENSP00000289473
RefSeq:
NP_000256.4
|
Others |
UniRef100:
UniRef100_P14598
UniRef90:
UniRef90_P14598
UniRef50:
UniRef50_P14598
UniGene:
Hs.647047,
Hs.655201
CCDS:
CCDS34657.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员