| Type | Description |
|---|---|
| Definition | solute carrier family 5 member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans. | 33416451 |
| 2021-02-06 13:53:00 | Sodium-Dependent Glucose Transporter 1 (SGLT1) Stabled by HER2 Promotes Breast Proliferation by Activation of the PI3K/Akt/mTOR Signaling Pathway in HER2+ Breast Cancer. | 32377271 |
| 2020-12-12 13:22:00 | Expression of glucose transporters in duodenal mucosa of patients with type 1 diabetes. | 32617672 |
| 2020-05-02 12:05:00 | SGLT1 depletion results in decreased levels of phospho-EGFR, and as a result, the activity of downstream signalling pathways (such as AKT and ERK) is inhibited. Hence, targeting SGLT1 itself or the EGFR-SGLT1 interaction may provide novel therapeutics against triple-negative breast cancer. | 31199048 |
| 2020-04-11 12:34:00 | This study showed that SGLT2 mRNA expression was lower in diabetic kidney disease compared with controls or glomerulonephritis and inversely related to interstitial fibrosis. | 31545924 |
| Type | IDs |
|---|---|
| Synonymous | D22S675, NAGT, SGLT1 |
| Gene |
UniProtKB-ID:
SC5A1_HUMAN
UniprotKB:
P13866
UniParc:
UPI00001359EA,
UPI0001914F5D
EMBL:
L29328,
L29329,
L29332,
L29339,
M24847,
L29337,
AK297665,
Z74021,
L29331,
L29330,
L29334,
Z83849,
L29333,
AL022321,
L29338,
CH471095,
Z83839,
CR456579,
AK316184,
L29335,
L29336,
Z80998,
AK312948
Ensembl:
ENSG00000100170
KO:
hsa:6523
|
| Nucleutide sequences |
EMBL-CDS:
BAG35789.1,
AAB59448.1,
CAG30465.1,
AAA60320.1,
EAW60006.1,
BAH12645.1,
BAH14555.1
Ensembl_TRS:
ENST00000543737,
ENST00000266088
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000444898,
ENSP00000266088
RefSeq:
NP_001243243.1,
NP_000334.1,
XP_011528633.1
|
| Others |
UniRef100:
UniRef100_P13866
UniRef90:
UniRef90_P13866
UniRef50:
UniRef50_P13866
UniGene:
Hs.1964
CCDS:
CCDS13902.1,
CCDS58805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员