| Type | Description |
|---|---|
| Definition | NAD kinase |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:03:00 | These data indicate that Akt-mediated phosphorylation of NADK stimulates its activity to increase NADP(+) production through relief of an autoinhibitory function inherent to its amino terminus. | 30846598 |
| 2017-12-16 12:11:00 | Data indicate metabolic enzymes NAD kinase and ketohexokinase as candidate metabolic gene targets, and the chromatin remodeling protein INO80C as a tumor suppressor in KRAS(MUT) colorectal tumor xenograft. | 28954733 |
| 2016-06-11 11:56:00 | Depletion of wild-type NADK in pancreatic ductal adenocarcinoma cells attenuates cancer cell growth. | 26806015 |
| 2016-04-23 10:43:00 | Taken together, this indicates that Ser-188 (and perhaps the other residues) is an important phosphorylation site that can downregulate the NAD kinase activity of this critical enzyme. | 26577408 |
| 2011-12-10 10:27:00 | Using purified human NAD kinase, we revealed a sigmoidal kinetic behavior toward ATP and the inhibitory effects of NADPH and NADH | 21526340 |
| Type | IDs |
|---|---|
| Synonymous | dJ283E3.1 |
| Gene |
UniProtKB-ID:
NADK_HUMAN,
A0A0A0MR98_HUMAN,
A0A024R058_HUMAN,
Q6PJ22_HUMAN
UniprotKB:
O95544,
A0A0A0MR98,
A0A024R058,
Q6PJ22
UniParc:
UPI00003534ED,
UPI00001320B0,
UPI00033362A3,
UPI000013CBEB,
UPI0001E92A3A
EMBL:
AF250320,
BC001709,
AL031282,
AK296722,
CH471183,
AY090771,
BC024219,
AK023114,
AK290161
Ensembl:
ENSG00000008130
KO:
hsa:65220
|
| Nucleutide sequences |
EMBL-CDS:
AAG44568.1,
BAH12420.1,
BAF82850.1,
AAH01709.1,
EAW56152.1,
BAB14412.1,
EAW56151.1,
AAM01195.1,
EAW56153.1,
EAW56155.1,
AAH24219.1
Gene_ORFName:
hCG_2033593
Ensembl_TRS:
ENST00000341991,
ENST00000341426,
ENST00000378625,
ENST00000342348
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367890,
ENSP00000341679,
ENSP00000344340,
ENSP00000339727
RefSeq:
XP_006710902.1,
NP_001185923.1,
XP_011540308.1,
XP_016857632.1,
NP_001340570.1,
NP_001185922.1,
NP_001340571.1,
XP_016857635.1,
NP_001185924.1,
XP_016857634.1,
XP_011540309.1,
XP_011540310.1,
NP_075394.3,
XP_016857633.1,
XP_011540311.1
|
| Others |
UniRef100:
UniRef100_Q6PJ22,
UniRef100_A0A0A0MR98,
UniRef100_O95544
UniRef90:
UniRef90_Q6PJ22,
UniRef90_O95544,
UniRef90_O95544-3
UniRef50:
UniRef50_O95544,
UniRef50_Q6PJ22
UniGene:
Hs.654792,
Hs.731532,
Hs.733075
CCDS:
CCDS30565.1,
CCDS55562.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员