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6522 SLC4A2

6522

SLC4A2

solute carrier family 4 member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 4 member 2

研究结论

Date Results Publications
2019-03-02 11:07:00 Study found that AE2 was overexpressed in ovarian cancer samples, and up-regulated AE2 expression can activate the mTOR/p70S6K1 pathway, promoting ovarian cancer cell growth. 28743911
2018-12-22 12:13:00 The regulation of a basolateral located, DIDS-sensitive, Cl(-)/HCO3(-) exchanger, anion exchanger 2 (AE2; SLC4A2) which is postulated to act as an acid loader, and therefore potential regulator of HCO3(-) secretion, in human airway epithelial cells. 28455748
2018-01-27 12:10:00 To match the stimulatory effect on acid uptake, cell-to-cell coupling in NHDF-Ad and CCD-112-CoN cells was strengthened with TGFbeta1.Importantly, the activities of stromal AE2 and connexin-43 do not place an energetic burden on cancer cells, allowing resources to be diverted for other activities 27543333
2017-09-30 11:13:00 ABA transport in human nucleated cells occurs via the anion exchanger AE2 27015766
2017-07-22 10:32:00 down-regulation in primary biliary cholangitis sensitizes cholangiocytes to apoptotic insults by activating soluble adenylyl cyclase 26991014

名称对应

Type IDs
Synonymous AE2, BND3L, EPB3L1, HKB3, NBND3
Gene
UniProtKB-ID: B3A2_HUMAN, Q59GF1_HUMAN
UniprotKB: P04920, Q59GF1
UniParc: UPI00004F6BBD, UPI000002A49A, UPI000013EFE9, UPI0001B792F5
EMBL: CH471173, AB209158, AK295767, AK312699, X62137, BC009434, BC009386, X03918, DQ149844, AC010973
Ensembl: ENSG00000164889
KO: hsa:6522
Nucleutide sequences
EMBL-CDS: EAW54046.1, EAW54047.1, AAH09386.1, AAZ38724.1, CAA44067.1, CAA27556.1, BAG35577.1, AAH09434.1, BAG58592.1, BAD92395.1
Ensembl_TRS: ENST00000413384, ENST00000485713, ENST00000392826, ENST00000461735
Protein sequencees
Ensembl_PRO: ENSP00000376571, ENSP00000419164, ENSP00000405600, ENSP00000419412
RefSeq: XP_006716157.1, NP_001186622.1, NP_001186623.1, NP_001186621.1, NP_003031.3
Others
UniRef100: UniRef100_P04920
UniRef90: UniRef90_P04920
UniRef50: UniRef50_P04920
UniGene: Hs.647069
CCDS: CCDS56521.1, CCDS5917.1, CCDS56520.1

全选

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研究热度

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