| Type | Description |
|---|---|
| Definition | calponin 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 10:43:00 | Oxidative stress may contribute to the increase in aortic MMP-2 activity, possibly by S-glutathiolation, and this may result in calponin-1 loss and maladaptive vascular remodeling in early hypertension. | 30339939 |
| 2018-02-03 11:42:00 | MMP-2 activity is increased in both conductance and resistance arteries in hypertension and contributes to early vascular dysfunction and remodelling. These maladaptive effects were related to the divergent regulation of calponin-1, which is decreased in aortas while is increased in resistance arteries. | 28374979 |
| 2017-08-12 12:25:00 | Actin cytoskeleton depolymerization inhibites BMP2 signaling via blocking of Smad by dephosphorylated CNN1 in osteoblast cells under simulated microgravity. | 28457943 |
| 2017-05-06 20:39:00 | Data suggest that proteolysis of calponin-1 by Mmp2 (matrix metallopeptidase 2) contributes to the down-regulation of calponin-1 in cytoplasm of endothelium and smooth muscle of aorta/arteries in early (1-week) hypertension; however, at 2-weeks, calponin-1 is up-regulated. | 27531060 |
| 2015-04-11 12:35:00 | Calponin 1 is present in the cervix of virgin, 11 day, and 20 day pregnant rats. | 25108144 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CNN1_RAT
UniprotKB:
Q08290
UniParc:
UPI0000127AE9
EMBL:
D14437,
BC061809,
X71071
Ensembl:
ENSRNOG00000027736
KO:
rno:65204
|
| Nucleutide sequences |
EMBL-CDS:
AAH61809.1,
CAA50397.1,
BAA03320.1
Ensembl_TRS:
ENSRNOT00000029577
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000029782
RefSeq:
NP_113935.2
|
| Others |
UniRef100:
UniRef100_Q08290
UniRef90:
UniRef90_Q08091
UniRef50:
UniRef50_Q08093
UniGene:
Rn.31788
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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