| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily D member 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | Over-expression of Kv4.3 gene reverses cardiac remodeling and transient-outward K(+) current (Ito) reduction via CaMKII inhibition in myocardial infarction. | 33254430 |
| 2020-02-01 11:18:00 | Immunogold staining and electron microscopy of heart vibrosections was performed to localize Kv4.2/Kv4.3 and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) proteins. Patch-Clamp recordings in control conditions and after lipid raft or caveolae disruption show that the CaMKII-Kv4 channel complex must associate in non-caveolar lipid rafts to be functional. | 31935048 |
| 2020-01-11 11:04:00 | Kv4.3 reduction is an important mediator in cardiac hypertrophy development via excessive CaMKII activation. | 30462989 |
| 2018-10-27 10:27:00 | down-regulation of Kv4.3 channels mediating A-type K(+) (IA) currents currents in nociceptive V2 trigeminal neurons is an underlying mechanism of oxaliplatin-induced orofacial neuropathic pain. | 29313436 |
| 2017-08-19 12:55:00 | NMDA reduced both currents in a concentration-dependent manner, whereas there was no significant impact on the currents when perfused with MK-801. MDD rats exhibited significantly more fibrosis areas in heart tissue and reduced expression of Kv4.2, Kv4.3, and Cav1.2. | 28566490 |
| Type | IDs |
|---|---|
| Synonymous | Kv4.3 |
| Gene |
UniProtKB-ID:
KCND3_RAT,
A0A0G2JSW5_RAT,
A0A0G2JSN5_RAT
UniprotKB:
Q62897,
A0A0G2JSW5,
A0A0G2JSN5
UniParc:
UPI000021C4F0,
UPI00000E7D2F,
UPI000021C4EF,
UPI00000E8729,
UPI000021C4EE
EMBL:
U92897,
AF334791,
L48619,
AB003587,
AABR07012775,
AABR07012774,
U42975,
U75448
Ensembl:
ENSRNOG00000014686
KO:
rno:65195
|
| Nucleutide sequences |
EMBL-CDS:
BAA24525.1,
AAA80459.1,
AAB18337.1,
AAK07651.1,
AAB53321.1,
AAC52695.1
Ensembl_TRS:
ENSRNOT00000047827,
ENSRNOT00000051835,
ENSRNOT00000019997
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000041746,
ENSRNOP00000049111,
ENSRNOP00000019997
RefSeq:
NP_001257891.1,
NP_113927.2,
NP_001257892.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JSW5,
UniRef100_Q62897,
UniRef100_A0A0G2JSN5
UniRef90:
UniRef90_Q62897,
UniRef90_Q62897-2
UniRef50:
UniRef50_Q63881,
UniRef50_Q62897-2
UniGene:
Rn.10540,
Rn.214215
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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