| Type | Description |
|---|---|
| Definition | LIM domain kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 13:11:00 | We demonstrated that LIMK1, as one target of miR-27b, might mediate sevoflurane-induced synapse deficits in the hippocampus. These results emphasize the potential role of LIMK1 in cognitive dysfunction in rats. | 27973945 |
| 2017-09-02 10:44:00 | MiR-134-mediated LIM domain kinase was involved in Regulates Hippocampal Synaptic Plasticity via miR-134-mediated LIMK1 function in rats with ischemic stroke induced hippocampal synaptic plasticity, which served as a contributor to improving learning and memory during the recovery stage of ischemic stroke. | 28116173 |
| 2015-02-21 10:17:00 | Data indicate that LIM motif-containing protein kinases LIMK1 and LIMK2-dependent acin rearrangement is involved in the development of complete Freund's adjuvant (CFA)-induced inflammatory pain. | 24962708 |
| 2014-12-20 13:08:00 | the functional relevance of the LRAP25-MRCK complex in LIMK1-cofilin signaling and the importance of LRAP adaptors as key determinants of MRCK cellular localization and downstream specificities. | 25107909 |
| 2014-10-11 10:50:00 | the CaMKIIbeta phosphorylates LIMK1 at Thr-508 in the kinase domain and activates the cofilin-phosphorylating activity of LIMK1. | 23600483 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G3V663_RAT
UniprotKB:
G3V663
UniParc:
UPI000019B61A
EMBL:
AC135741,
CH473973
Ensembl:
ENSRNOG00000001470
KO:
rno:65172
|
| Nucleutide sequences |
EMBL-CDS:
EDM13417.1,
EDM13416.1
Gene_ORFName:
rCG_21136
Ensembl_TRS:
ENSRNOT00000001996,
ENSRNOT00000084427
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073078,
ENSRNOP00000001996
RefSeq:
XP_006249247.1,
NP_113915.2
|
| Others |
UniRef100:
UniRef100_G3V663
UniRef90:
UniRef90_P53667
UniRef50:
UniRef50_P53667
UniGene:
Rn.11250
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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