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65162 Dio2

65162

Dio2

iodothyronine deiodinase 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition iodothyronine deiodinase 2

研究结论

Date Results Publications
2017-10-07 10:20:00 Glucocorticoids inhibited the adrenergic stimulation of Dio2 at the transcriptional level in brown adipocytes. 26994513
2016-12-17 11:01:00 This study demonstrated that reduction of the Dio2 mRNA expression in hippocampus of thyroidectomized Wistar rats. 26861177
2015-04-11 13:35:00 These studies reveal that tissue-specific differences in D2 ubiquitination are an inherent property of the TRH/TSH feedback mechanism 25555216
2015-02-28 12:51:00 cold exposure is accompanied by concerted changes in the metabolism of BAT and oxidative and glycolytic skeletal muscles that are paralleled by type 2 deiodinase activation 25294216
2015-01-03 10:36:00 results of the present study hypothesize that progesterone withdrawal may underlie the decrement in D2 expression, with consequent reduction in the peripheral conversion of T4 into T3 leading to a hypothyroid state. 24362948

名称对应

Type IDs
Synonymous 5DII, DIOII
Gene
UniProtKB-ID: IOD2_RAT
UniprotKB: P70551
UniParc: UPI00006027FF
EMBL: AB011068, U53505
KO: rno:65162
Nucleutide sequences
EMBL-CDS: BAA25186.1, AAC52767.1
Protein sequencees
RefSeq: NP_113908.4
Others
UniRef100: UniRef100_P70551
UniRef90: UniRef90_P70551
UniRef50: UniRef50_Q92813
UniGene: Rn.88380

全选

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研究热度

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