| Type | Description |
|---|---|
| Definition | WNK lysine deficient protein kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:26:00 | Silencing of long noncoding RNA LEF1-AS1 prevents the progression of hepatocellular carcinoma via the crosstalk with microRNA-136-5p/WNK1. | 32068261 |
| 2021-02-20 13:36:00 | Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis. | 32790646 |
| 2020-12-19 13:42:00 | A novel biallelic single base insertion in WNK1 in a Pakistani family with congenital insensitivity to pain. | 32127623 |
| 2020-07-25 11:12:00 | These results indicated that miRNA-524-5p inhibited angiogenesis in colon cancer cells via targeting WNK1. | 32174132 |
| 2020-05-23 11:16:00 | The inhibition of WNK1-mediated TRPC6 activation and its downstream substrate calcineurin attenuated NFATc1 activation. | 31022353 |
| Type | IDs |
|---|---|
| Synonymous | HSAN2, HSN2, KDP, PPP1R167, PRKWNK1, PSK, p65 |
| Gene |
UniProtKB-ID:
WNK1_HUMAN,
A5D8Z4_HUMAN,
F5GWT4_HUMAN
UniprotKB:
Q9H4A3,
A5D8Z4,
F5GWT4
UniParc:
UPI0001D411C7,
UPI0001DD21C4,
UPI000151931C,
UPI00024C03E8,
UPI0000366853,
UPI0001D411C5,
UPI000013CD65,
UPI0000E593D0
EMBL:
BC130469,
AJ296290,
FJ515833,
AC004765,
BC013629,
AF061944,
AC004803,
BK004108,
AB002342,
AY231477,
JQ358908,
BC130467,
BC141881
Ensembl:
ENSG00000060237
KO:
hsa:65125
|
| Nucleutide sequences |
EMBL-CDS:
AAI30470.1,
AEY99342.1,
BAA20802.2,
AAH13629.2,
AAI30468.1,
ACS13727.1,
ACS13726.1,
AAO46160.1,
AAF31483.1,
CAC15059.1,
ACS13728.1,
DAA04494.1,
AAI41882.1
Ensembl_TRS:
ENST00000537687,
ENST00000315939,
ENST00000530271,
ENST00000340908,
ENST00000535572
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000313059,
ENSP00000341292,
ENSP00000444465,
ENSP00000433548,
ENSP00000441972
RefSeq:
NP_998820.3,
XP_011519300.1,
XP_011519311.1,
XP_011519308.1,
XP_011519302.1,
NP_055638.2,
XP_011519299.1,
XP_011519309.1,
XP_016875323.1,
XP_016875325.1,
XP_016875327.1,
XP_011519303.1,
XP_011519305.1,
NP_001171914.1,
XP_011519304.1,
XP_011519307.1,
XP_016875326.1,
XP_016875328.1,
NP_061852.3,
XP_006719066.1,
XP_011519306.1,
XP_011519301.1,
XP_016875324.1,
XP_011519310.1
|
| Others |
UniRef100:
UniRef100_Q9H4A3,
UniRef100_F5GWT4,
UniRef100_A5D8Z4
UniRef90:
UniRef90_A5D8Z4,
UniRef90_Q9H4A3,
UniRef90_F5GWT4
UniRef50:
UniRef50_A0A452QFQ9,
UniRef50_Q9H4A3,
UniRef50_Q9H4A3-2
UniGene:
Hs.744906
CCDS:
CCDS8506.1,
CCDS73419.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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