| Type | Description |
|---|---|
| Definition | Nedd4 family interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:09:00 | NDFIP1 mediates a CD8(+) T cell tolerance checkpoint. | 30021156 |
| 2018-11-24 11:24:00 | Ndfip1 preserves Treg lineage stability and immune homeostasis by preventing the expansion of highly proliferative and metabolically active Treg cells and by preventing pathological secretion of IL-4 from Treg cells | 28580955 |
| 2018-10-20 10:13:00 | Data support an essential role for Ndfip1 in degrading RORgammaT and suppressing Th17 lineage stability, proinflammatory cytokine production, and pathogenicity. | 28051111 |
| 2018-09-01 10:44:00 | Findings indicate an important negative regulatory function for Nedd4 ubiquitin protein ligase (Nedd4-2) and Nedd4 family interacting protein 1 (Ndfip1) in IgE-dependent mast cell activity. | 27786273 |
| 2016-09-10 10:27:00 | Data indicate thar Janus kinase 1 (Jak1) degradation is dependent on Nedd4 family interacting proteins Ndfip1/Ndfip2. | 27088444 |
| Type | IDs |
|---|---|
| Synonymous | 0610010M22Rik, N4wbp5 |
| Gene |
UniProtKB-ID:
NFIP1_MOUSE
UniprotKB:
Q8R0W6
UniParc:
UPI0000027D02
EMBL:
AK050560,
AF220209,
BC026372
Ensembl:
ENSMUSG00000024425
KO:
mmu:65113
|
| Nucleutide sequences |
EMBL-CDS:
BAC34324.1,
AAG44248.1,
AAH26372.1
Ensembl_TRS:
ENSMUST00000236085,
ENSMUST00000025293
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158314,
ENSMUSP00000025293
RefSeq:
NP_075372.1,
NP_001342678.1
|
| Others |
UniRef100:
UniRef100_Q8R0W6
UniRef90:
UniRef90_Q8R0W6
UniRef50:
UniRef50_Q8R0W6
UniGene:
Mm.102496
CCDS:
CCDS37789.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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