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65113 Ndfip1

65113

Ndfip1

Nedd4 family interacting protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition Nedd4 family interacting protein 1

研究结论

Date Results Publications
2019-12-07 10:09:00 NDFIP1 mediates a CD8(+) T cell tolerance checkpoint. 30021156
2018-11-24 11:24:00 Ndfip1 preserves Treg lineage stability and immune homeostasis by preventing the expansion of highly proliferative and metabolically active Treg cells and by preventing pathological secretion of IL-4 from Treg cells 28580955
2018-10-20 10:13:00 Data support an essential role for Ndfip1 in degrading RORgammaT and suppressing Th17 lineage stability, proinflammatory cytokine production, and pathogenicity. 28051111
2018-09-01 10:44:00 Findings indicate an important negative regulatory function for Nedd4 ubiquitin protein ligase (Nedd4-2) and Nedd4 family interacting protein 1 (Ndfip1) in IgE-dependent mast cell activity. 27786273
2016-09-10 10:27:00 Data indicate thar Janus kinase 1 (Jak1) degradation is dependent on Nedd4 family interacting proteins Ndfip1/Ndfip2. 27088444

名称对应

Type IDs
Synonymous 0610010M22Rik, N4wbp5
Gene
UniProtKB-ID: NFIP1_MOUSE
UniprotKB: Q8R0W6
UniParc: UPI0000027D02
EMBL: AK050560, AF220209, BC026372
Ensembl: ENSMUSG00000024425
KO: mmu:65113
Nucleutide sequences
EMBL-CDS: BAC34324.1, AAG44248.1, AAH26372.1
Ensembl_TRS: ENSMUST00000236085, ENSMUST00000025293
Protein sequencees
Ensembl_PRO: ENSMUSP00000158314, ENSMUSP00000025293
RefSeq: NP_075372.1, NP_001342678.1
Others
UniRef100: UniRef100_Q8R0W6
UniRef90: UniRef90_Q8R0W6
UniRef50: UniRef50_Q8R0W6
UniGene: Mm.102496
CCDS: CCDS37789.1

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