| Type | Description |
|---|---|
| Definition | prostate transmembrane protein, androgen induced 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:48:00 | Pmepa1 expression was barely detected in osteoclasts formed on plastic surfaces in vitro, but was markedly increased in activated osteoclasts formed on calcified matrix. Inhibitors of bone resorption suppressed its expression. Pmepa1 protein localized to lysosomes in osteoclasts. | 30557043 |
| 2018-12-22 12:17:00 | Pmepa1 is induced by RANK-p38 MAPK pathway signaling. | 28802000 |
| 2018-01-20 11:41:00 | binding of SMAD2/3, the intracellular effectors of activin signaling, was significantly enriched at the Pmepa1 gene, which encodes a negative feedback regulator of TGF-beta signaling in cancer cells, and at the Kdm6b gene, which encodes an epigenetic regulator promoting transcriptional plasticity. | 26215835 |
| 2011-01-01 11:14:00 | Wnt/beta-catenin/TCF7L2 pathway is preferentially able to alter the transcriptional regulation of the TGF-beta-target gene, TMEPAI. | 20889500 |
| Type | IDs |
|---|---|
| Synonymous | 2210418I02Rik, AW455466, Erg1.2, N4wbp4, Stag1, Tmepai |
| Gene |
UniProtKB-ID:
A2APF4_MOUSE
UniprotKB:
A2APF4
UniParc:
UPI000004970D
EMBL:
AL837509,
AL837520
Ensembl:
ENSMUSG00000038400
KO:
mmu:65112
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000036248
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039950
RefSeq:
NP_075371.2,
XP_006500054.1
|
| Others |
UniRef100:
UniRef100_A2APF4
UniRef90:
UniRef90_Q9D7R2
UniRef50:
UniRef50_Q969W9
UniGene:
Mm.73682
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30557043 |
FASEB J. Xianghe Xu , Hirohito Hirata , Makoto Shiraki , Asana Kamohara , Kenichi Nishioka , Hiroshi Miyamoto , Toshio Kukita , Akiko Kukita |
2019-03-01 | - |
| 28802000 |
Pmepa1 induced by RANKL-p38 MAPK pathway has a novel role in osteoclastogenesis. J. Cell. Physiol. Noboru Funakubo , Xianghe Xu , Toshio Kukita , Seiji Nakamura , Hiroshi Miyamoto , Akiko Kukita |
2018-04-01 | - |
| 26215835 |
Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling. Mol. Neurobiol. Andrea S Link , Svitlana Kurinna , Steven Havlicek , Sandra Lehnert , Martin Reichel , Johannes Kornhuber , Beate Winner , Tobias Huth , Fang Zheng , Sabine Werner , Christian Alzheimer |
2016-08-01 | - |
| 26238476 |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev. Biol. Jordan P Lewandowski , Fang Du , Shilu Zhang , Marian B Powell , Kristin N Falkenstein , Hongkai Ji , Steven A Vokes |
2015-10-01 |
Pkdcc,
Tecr,
Osr2,
Ap1s2,
Pmch,
Ppp2r4,
Alx4,
Apoa2,
Aprt,
Avpr2,
Prdm1,
Bmp2,
Bmp4,
Bmpr1b,
Runx3,
Cdk6,
Cntfr,
Dcn,
Dlk1,
Dlx5,
Drd3,
Ebf3,
Sparcl1,
Ednrb,
Efna1,
Eomes,
Epha3,
Foxf2,
Fzd7,
Gata5,
Gli1,
Grcc10,
Hand2,
Hccs,
Foxf1,
Hhip,
Hmga1,
Hoxa7,
Hoxb4,
Hoxc4,
Hoxd10,
Hoxd11,
Hoxd13,
Id3,
Ier2,
Ier5,
Igf1r,
Inha,
Irx3,
Isl1,
Jag1,
Kit,
Klf3,
Klf9,
Lum,
Xpnpep2,
Zfp704,
Slc8b1,
Smad7,
Meis1,
Mgmt,
Meis2,
Polr2k,
Myl4,
Nfe2l3,
Cldn11,
Pam,
Pax1,
Pax9,
Pbx1,
Enpp1,
Prkce,
Ptch1,
Ptch2,
Igdcc3,
Aldh1a2,
Mrpl23,
Sfrp2,
Shcbp1,
Slc2a1,
Ncor2,
Sox4,
Sp1,
Sall3,
Depdc7,
Pqlc2,
Tank,
Tbx2,
Tbx3,
Tbx4,
Lrrc20,
Tmem5,
Tcte3,
Stxbp6,
Tpd52l1,
Wnt11,
Cyyr1,
Xpa,
Zfp281
|
| 25410786 |
Dev. Dyn. Md Nurul Islam , Shinsuke Itoh , Takeshi Yanagita , Kumi Sumiyoshi , Satoru Hayano , Koh-Ichi Kuremoto , Hiroshi Kurosaka , Tadashi Honjo , Noriaki Kawanabe , Hiroshi Kamioka , Takayoshi Sakai , Naozumi Ishimaru , Ichiro Taniuchi , Takashi Yamashiro |
2015-03-01 |
Crisp3,
Amy1,
Aqp5,
Runx2,
Runx1,
Runx3,
Cbfb,
Egf,
Klk1,
Krt14,
Ngf,
Pmepa1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20889500 |
Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene. J Biol Chem Naoko Nakano , Susumu Itoh , Yukihide Watanabe , Kota Maeyama , Fumiko Itoh , Mitsuyasu Kato |
2010-12-03 | - |
| 20129061 |
Mol. Cell Yukihide Watanabe , Susumu Itoh , Toshiyasu Goto , Eriko Ohnishi , Masako Inamitsu , Fumiko Itoh , Kiyotoshi Satoh , Eliza Wiercinska , Weiwen Yang , Liang Shi , Aya Tanaka , Naoko Nakano , A Mieke Mommaas , Hiroshi Shibuya , Peter Ten Dijke , Mitsuyasu Kato |
2010-01-15 |
Pmepa1,
SMAD2,
SMAD3,
PMEPA1
|
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 17967808 |
EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst |
2007-09-01 |
Gm11696,
Gm10589,
Apela,
Gm10822,
Gm2085,
Gm2312,
Lncenc1,
Gm2381,
Gm2659,
Gm2679,
Dynlt1c,
Gm3134,
Gm3143,
Gm3236,
Gm3574,
Gm3581,
Gm3718,
Gm3859,
Gm3905,
Gm3952,
Gm3957,
Gm3973,
Gm12057,
Rex2,
Gm4218,
Gm4225,
Gm16476,
Gm4407,
Gm14410,
Gm4420,
Gm14005,
1300002E11Rik,
Gm4532,
Srcap,
Gm17789,
Gm10751,
Gm14321,
0610009E02Rik,
Gm12758,
Gm11532,
Phactr4,
Rusc2,
AK010878,
Gm10778,
5830417I10Rik,
Mir1902,
Gm15270,
Gm11767,
Ino80dos,
Bsdc1,
Gm7645,
Gm20590,
Slc44a1,
Gm15545,
Gm17292,
2900009J06Rik,
Kifc1,
Gm13150,
Gm19426,
Gm19428,
Gm19474,
Gm14963,
Gm19565,
Gm19592,
Gm12588,
Snhg4,
Gm19702,
Gm19705,
Platr22,
Nuggc,
Zfp534,
Gm19860,
Gm11725,
Gm19876,
Gm19889,
Gm16201,
Gm13056,
Tnfsf13os,
Gm19925,
Gm19976,
Gm20014,
Gm16740,
Gm20039,
Gm20045,
AU020206,
Ccdc170,
Trp53cor1,
Gm20266,
Gm20324,
Zfp518b,
Gm14401,
AI480526,
Pds5b,
Ube3c,
Gm21297,
Akap9,
Gm29724,
Itfg2,
Parp11
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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