| Type | Description |
|---|---|
| Definition | VPS33A core subunit of CORVET and HOPS complexes |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 10:18:00 | Since the inhibition of autolysosome formation plays a critical role in tuberculosis occurrence, these fi ndings suggests that miR-423-5p could suppress autophagosome-lysosome fusion by post-transcriptional regulation of VPS33A, which might be important for the occurrence of active tuberculosis. | 30898038 |
| 2019-06-01 11:56:00 | It identified multimodal regulation of SNARE assembly by the Sec1/Munc18 (SM) protein VPS33A, mirroring other syntaxin-SM interactions and therefore suggesting a unified model of SM regulation. | 30655294 |
| 2017-09-30 13:41:00 | Mutations in VPS33A is associated with mucopolysaccharidosis with severe systemic symptoms. | 28013294 |
| 2017-09-09 14:43:00 | Data suggest that accumulation of autophagosomes confers cytotoxicity in a number of cell types including neurons mimicking neurodegeneration; RNA interference of combinations of MTOR, VPS33A, and STX17 lead to accumulation of autophagosomes and cytotoxicity. (MTOR = mechanistic target of rapamycin kinase; VPS33A = vacuolar protein sorting 33A; STX17 = syntaxin 17) | 28673965 |
| 2017-02-18 11:51:00 | The clinical phenotype and genetic studies support the suggestion that the siblings most probably have a novel disease very likely caused by a VPS33A gene defect. | 27547915 |
| Type | IDs |
|---|---|
| Synonymous | MPSPS |
| Gene |
UniProtKB-ID:
VP33A_HUMAN
UniprotKB:
Q96AX1
UniParc:
UPI000000D7AA
EMBL:
BC016617,
AF439857,
AK026840,
CH471054
Ensembl:
ENSG00000139719
KO:
hsa:65082
|
| Nucleutide sequences |
EMBL-CDS:
BAB15570.1,
AAL33577.1,
EAW98319.1,
AAH16617.1
Ensembl_TRS:
ENST00000267199
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000267199
RefSeq:
NP_075067.2,
NP_001337947.1,
NP_001337950.1,
NP_001337949.1,
NP_001337948.1
|
| Others |
UniRef100:
UniRef100_Q96AX1
UniRef90:
UniRef90_Q96AX1
UniRef50:
UniRef50_Q96AX1
UniGene:
Hs.592009
CCDS:
CCDS9231.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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