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65059 RAPH1

65059

RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

研究结论

Date Results Publications
2019-01-12 11:21:00 High RAPH1 expression is correlated with aggressive breast cancer phenotypes and provides independent prognostic value in invasive breast cancer. 30056565
2017-05-27 10:10:00 The human RAPH1 gene is the CHE2 locus. 27346732
2016-12-17 12:07:00 these studies demonstrate an insight into how the Lpd-PH domain regulates cellular signals in a PI(3,4)P2 dependent manner. 26726010
2016-06-28 11:17:00 Disruption of the RIAM/lamellipodin-integrin-talin complex markedly impairs cell migration. 26419705
2016-05-14 10:11:00 The authors propose that Lpd delivers Ena/VASP proteins to growing barbed ends and increases their actin polymerase activity by tethering them to actin filaments. 26295568

名称对应

Type IDs
Synonymous ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6
Gene
UniProtKB-ID: RAPH1_HUMAN, C9K0J5_HUMAN
UniprotKB: Q70E73, C9K0J5
UniParc: UPI000007003C, UPI00005E273C, UPI00005E273B, UPI000022BDD5, UPI00005E273D, UPI00005E2739, UPI000020940E, UPI000022BDD4, UPI000020940F, UPI00005E273A
EMBL: AY523978, AB053311, CH471063, AC018891, AJ584699, AY523977, AY494951, AB051468
Ensembl: ENSG00000173166
KO: hsa:65059
Nucleutide sequences
EMBL-CDS: BAB21772.1, AAY14676.1, BAB69020.1, CAE48361.1, AAS82582.1, AAS16935.1, AAS16936.1, EAW70345.1
Gene_ORFName: hCG_2043066
Ensembl_TRS: ENST00000453034, ENST00000319170, ENST00000439222, ENST00000419464, ENST00000418114, ENST00000308091, ENST00000423104, ENST00000374493, ENST00000630330
Protein sequencees
Ensembl_PRO: ENSP00000397751, ENSP00000411138, ENSP00000390578, ENSP00000316543, ENSP00000311293, ENSP00000406662, ENSP00000396711, ENSP00000363617, ENSP00000486548
RefSeq: XP_011509949.1, XP_005246834.1, XP_011509950.1, XP_011509948.1, XP_005246836.1, NP_976241.1, NP_998754.1, NP_001316657.1, XP_006712758.1
Others
UniRef100: UniRef100_C9K0J5, UniRef100_Q70E73
UniRef90: UniRef90_Q70E73
UniRef50: UniRef50_Q70E73
UniGene: Hs.471162
CCDS: CCDS2360.1, CCDS2359.1

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