| Type | Description |
|---|---|
| Definition | MER proto-oncogene, tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 10:12:00 | The long-term preservation of photoreceptors we observed indicates that MERTK-related form of inherited retinal degeneration, which has currently no cure, could be amenable to laser therapy or subretinal surgery, to extend the visual function, potentially for life. | 30054542 |
| 2019-06-15 10:19:00 | Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. We present here a comprehensive review of all reported MERTK disease causing variants with the associated phenotype | 29659094 |
| 2018-02-10 12:08:00 | Mertk protein expression in the Bone marrow mesenchymal stem cells was similar to that in the retinal pigment epithelial cells in the primary passage. | 28210098 |
| 2017-09-30 12:10:00 | study concludes that activated microglia release Gal-3 and a neuraminidase that desialylates microglial and PC12 surfaces, enabling Gal-3 binding to PC12 (neuron-like) cells and their phagocytosis via Mer tyrosine kinase (MerTK). | 28500071 |
| 2016-06-28 11:27:00 | This study demonstrated that in Mertk mutation mice regulated the Expression pattern of Ccr2 and Cx3cr1. | 26458944 |
| Type | IDs |
|---|---|
| Synonymous | rdy |
| Gene |
UniProtKB-ID:
MERTK_RAT
UniprotKB:
P57097
UniParc:
UPI000012EF26
EMBL:
AF208235
Ensembl:
ENSRNOG00000017319
KO:
rno:65037
|
| Nucleutide sequences |
EMBL-CDS:
AAF44060.1
Ensembl_TRS:
ENSRNOT00000023419
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000023419
RefSeq:
NP_075232.1
|
| Others |
UniRef100:
UniRef100_P57097
UniRef90:
UniRef90_P57097
UniRef50:
UniRef50_Q12866
UniGene:
Rn.48789
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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