Type | Description |
---|---|
Definition | Src like adaptor |
Date | Results | Publications |
---|---|---|
2020-09-12 15:58:00 | SLAP Is a Negative Regulator of FcepsilonRI Receptor-Mediated Signaling and Allergic Response. | 31156621 |
2015-08-22 10:47:00 | results suggest that cytoplasm-specific transduction of the SH3 and SH2 domains of SLAP has a therapeutic potential of being an immunosuppressive reagent for the treatment of various autoimmune diseases | 25800872 |
2014-09-20 11:30:00 | Taken together the data demonstrate that SLAP negatively regulates wild-type c-Kit signaling, but not its oncogenic counterpart, indicating a possible mechanism by which the oncogenic c-Kit bypasses the normal cellular negative feedback control | 24284075 |
2013-06-29 11:21:00 | upon ligand stimulation SLAP stably associates with Flt3 through multiple phosphotyrosine residues in Flt3. SLAP mRNA is differentially expressed in different cancers and its expression significantly increased in patients carrying the Flt3-ITD mutation | 23300935 |
2012-10-20 10:20:00 | These data provide evidence for src-like adaptor protein-dependent regulation of CD3 zeta-chain in the fine control of TCR signaling. | 22798681 |
Type | IDs |
---|---|
Synonymous | SLA1, SLAP |
Gene |
UniProtKB-ID:
SLAP1_HUMAN
UniprotKB:
Q13239
UniParc:
UPI0000210625,
UPI0000210623,
UPI000004B144,
UPI0001914ED2,
UPI0001914E74
EMBL:
CR536537,
CH471060,
U30473,
AJ238591,
AF305872,
BC007042,
AK312584,
AK297423,
AK297519,
U44403,
AF235100,
D89077
Ensembl:
ENSG00000155926
KO:
hsa:6503
|
Nucleutide sequences |
EMBL-CDS:
BAA13758.1,
AAC50357.1,
AAC27662.1,
CAG38774.1,
AAH07042.1,
EAW92159.1,
BAG35478.1,
BAH12602.1,
BAH12578.1,
CAB53536.1
Ensembl_TRS:
ENST00000338087,
ENST00000517648,
ENST00000395352,
ENST00000427060,
ENST00000524345
|
Protein sequencees |
Ensembl_PRO:
ENSP00000378759,
ENSP00000337548,
ENSP00000394049,
ENSP00000428559,
ENSP00000427928
RefSeq:
NP_006739.2,
XP_016869228.1,
NP_001269894.1,
NP_001039022.2,
NP_001269893.1,
NP_001039021.1
|
Others |
UniRef100:
UniRef100_Q13239
UniRef90:
UniRef90_Q13239
UniRef50:
UniRef50_Q13239
UniGene:
Hs.75367
CCDS:
CCDS64977.1,
CCDS47923.1,
CCDS47922.1,
CCDS6370.1,
CCDS64978.1
|
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