例如:"NBL1", "4681", "drought"
收藏
64945 Cldn12

64945

Cldn12

claudin 12

protein-coding

Mus musculus

基因描述

Type Description
Definition claudin 12

研究结论

Date Results Publications
2020-12-05 13:03:00 Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability. 32197346
2020-04-18 11:59:00 Present study thus shows that claudin-12 is not essential in establishing or maintaining blood-brain barrier tight juctionss (TJs) integrity. Claudin-12 is rather expressed in cells that typically lack TJs suggesting that claudin-12 plays a role other than forming classical TJs 31511021
2012-12-05 21:23:00 Claudin-12 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area. 14698084
2010-09-27 11:16:00 1,25(OH)2D3 downregulates cadherin-17 and upregulates claudin-2 and claudin-12 in the intestine, suggesting that 1,25(OH)2D3, by regulating these epithelial cell junction proteins, can route calcium through the paracellular path 20214989
2010-01-21 00:00:00 These findings strongly suggest that claudin-2- and/or claudin-12-based tight junctions form paracellular Ca(2+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis. 18287530

名称对应

Type IDs
Gene
UniProtKB-ID: CLD12_MOUSE
UniprotKB: Q9ET43
UniParc: UPI00000EB98C
EMBL: AF247664, AK166110, AK132155, BC024057, AK049331, AK039672
Ensembl: ENSMUSG00000046798
KO: mmu:64945
Nucleutide sequences
EMBL-CDS: AAF98801.1, AAH24057.1, BAC30414.1, BAC33687.1, BAE21001.1, BAE38577.1
Ensembl_TRS: ENSMUST00000115445, ENSMUST00000179804, ENSMUST00000060947, ENSMUST00000115446
Protein sequencees
Ensembl_PRO: ENSMUSP00000136988, ENSMUSP00000061928, ENSMUSP00000111105, ENSMUSP00000111106
RefSeq: NP_075028.1, XP_030110610.1, XP_011238975.1, NP_001180590.1, NP_001180588.1, XP_006503661.1, NP_001180589.1, XP_011238976.1
Others
UniRef100: UniRef100_Q9ET43
UniRef90: UniRef90_P56749
UniRef50: UniRef50_P56749
UniGene: Mm.40132
CCDS: CCDS19074.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员