| Type | Description |
|---|---|
| Definition | signal-induced proliferation-associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 10:08:00 | SIPA1 promotes oral squamous cell carcinoma metastasis by regulating the ITGB1 and MMP7. | 28237246 |
| 2017-04-08 11:32:00 | Study shows that SIPA1 mRNA and protein expression are down-regulated in gastric cancer cells and correlate with tumor grading, invasion and lymph node metastasis as well as higher expression of VEGFA. Low SIPA1 levels in gastric cancer may then accelerate tumor development and progression by promoting VEGFA expression to increase vascular density. | 28362978 |
| 2017-02-18 11:38:00 | results suggest that SIPA1 and RRP1B germline polymorphisms are important for breast cancer prognosis | 26901824 |
| 2015-06-20 12:43:00 | Our results indicate, for the first time, that the SIPA1 -313A>G may have a prognostic role in unresected NSCLC making it a potential predictor of poor survival due to earlier progression. | 25352027 |
| 2015-06-20 11:32:00 | nuclear SIPA1 contributes to breast cancer cell invasion through the regulation of integrin beta1 signaling. | 24704834 |
| Type | IDs |
|---|---|
| Synonymous | SPA1 |
| Gene |
UniProtKB-ID:
SIPA1_HUMAN
UniprotKB:
Q96FS4
UniParc:
UPI0000135D8A
EMBL:
AB005666,
AF029789,
AF052238,
AF052235,
AF052236,
BC110353,
AF052233,
AF052234,
BC010492,
AF052237
Ensembl:
ENSG00000213445
KO:
hsa:6494
|
| Nucleutide sequences |
EMBL-CDS:
BAA22197.1,
AAC32547.1,
AAH10492.1,
AAI10354.1,
AAC32559.1
Ensembl_TRS:
ENST00000394224,
ENST00000534313
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377771,
ENSP00000436269
RefSeq:
NP_694985.29,
NP_006738.3,
XP_005274246.1
|
| Others |
UniRef100:
UniRef100_Q96FS4
UniRef90:
UniRef90_Q96FS4
UniRef50:
UniRef50_Q96FS4
UniGene:
Hs.530477
CCDS:
CCDS8108.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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