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64931 Izumo1r

64931

Izumo1r

IZUMO1 receptor, JUNO

protein-coding

Mus musculus

基因描述

Type Description
Definition IZUMO1 receptor, JUNO

研究结论

Date Results Publications
2020-09-19 16:22:00 Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice. 30816314
2018-09-15 10:13:00 JUNO interacts with IZUMO1 during sperm binding.Trp62 of JUNO interacts with hydrophobic residues on the alpha-helical core region of IZUMO1.Surface-exposed tryptophan residue of JUNO is required for sperm binding and fertilization. 27416963
2018-07-28 10:47:00 Juno was expressed in oocytes at the germinal vesicle stage and it continues to be expressed at similar levels in later stages of oocytes maturation. 29124919
2016-05-14 11:36:00 JUNO associates with monomeric IZUMO1, which is then quickly removed as tight adhesion of the two cells is subsequently established. 26568141
2014-11-29 12:09:00 Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilization. 25209248

名称对应

Type IDs
Synonymous 0910001L11Rik, C86255, Folbp3, Folr4, Juno
Gene
UniProtKB-ID: JUNO_MOUSE, Q8BY83_MOUSE, Q8BUM2_MOUSE
UniprotKB: Q9EQF4, Q8BY83, Q8BUM2
UniParc: UPI0000023916, UPI0000027990, UPI0001630CF3, UPI00000EAA05
EMBL: EU326437, AK083306, BC028431, AF250145, EU326438, AC136743, AK041596
Ensembl: ENSMUSG00000031933
KO: mmu:64931
Nucleutide sequences
EMBL-CDS: ABY56298.1, AAH28431.1, ABY56297.1, AAG36877.1, BAC30998.1, BAC38857.1
Ensembl_TRS: ENSMUST00000034409, ENSMUST00000069408
Protein sequencees
Ensembl_PRO: ENSMUSP00000034409, ENSMUSP00000063632
RefSeq: XP_006510596.1, XP_017168991.1, XP_006510594.1, XP_017168990.1, XP_006510599.1, XP_017168992.1, NP_075026.1, XP_006510593.1, XP_017168993.1, NP_789777.1
Others
UniRef100: UniRef100_Q8BUM2, UniRef100_Q8BY83, UniRef100_Q9EQF4
UniRef90: UniRef90_Q8BY83, UniRef90_Q9EQF4, UniRef90_Q8BUM2
UniRef50: UniRef50_Q8BUM2, UniRef50_Q9EQF4, UniRef50_Q8BY83
UniGene: Mm.86738
CCDS: CCDS22831.1

全选

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