Type | Description |
---|---|
Definition | tuberous sclerosis 1 |
Date | Results | Publications |
---|---|---|
2021-03-28 19:06:00 | Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived | 32927859 |
2021-01-16 15:58:00 | and Preosteoblast-Specific Ablation of TSC1 in Mice Lead to Severe and Slight Spinal Dysplasia, Respectively. | 32309432 |
2021-01-02 12:49:00 | Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer. | 31961824 |
2020-05-02 11:26:00 | Results found that osteocyte TSC1 disruption reduced sclerostin in bone, leading to osteosclerosis with enhanced bone formation in mice. TSC1 promotes sclerostin expression and prevents osteogenesis through inhibition of mTORC1 and downregulation of Sirt1. | 31088250 |
2020-05-02 10:06:00 | Loss of the tumor suppressor tuberous sclerosis complex 1 (Tsc1) in the liver promotes gluconeogenesis and glucose intolerance. | 31919282 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
TSC1_MOUSE
UniprotKB:
Q9EP53
UniParc:
UPI00000E5D6E,
UPI00000229FE,
UPI00005AC655,
UPI000019B046
EMBL:
AJ271912,
AB047561,
CH466542,
AJ271911,
AK147428,
AL731851,
AK122229,
BC052399
Ensembl:
ENSMUSG00000026812
KO:
mmu:64930
|
Nucleutide sequences |
EMBL-CDS:
BAE27905.1,
BAB60810.1,
BAC65511.1,
EDL08392.1,
AAH52399.1,
CAC20676.1,
CAC20677.1
Ensembl_TRS:
ENSMUST00000113869,
ENSMUST00000028155,
ENSMUST00000113870,
ENSMUST00000113867
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109501,
ENSMUSP00000109500,
ENSMUSP00000109498,
ENSMUSP00000028155
RefSeq:
XP_036018339.1,
XP_006498285.1,
XP_006498284.1,
XP_011237444.1,
XP_006498283.1,
XP_030107795.1,
NP_001276504.1,
XP_011237445.1,
NP_001276505.1,
XP_006498286.1,
XP_011237446.1,
NP_075025.2,
XP_030107796.1
|
Others |
UniRef100:
UniRef100_Q9EP53
UniRef90:
UniRef90_Q9EP53
UniRef50:
UniRef50_Q92574
UniGene:
Mm.224354
CCDS:
CCDS79762.1,
CCDS15844.1,
CCDS71013.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员