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64930 Tsc1

64930

Tsc1

tuberous sclerosis 1

protein-coding

Mus musculus

基因描述

Type Description
Definition tuberous sclerosis 1

研究结论

Date Results Publications
2021-03-28 19:06:00 Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived 32927859
2021-01-16 15:58:00 and Preosteoblast-Specific Ablation of TSC1 in Mice Lead to Severe and Slight Spinal Dysplasia, Respectively. 32309432
2021-01-02 12:49:00 Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer. 31961824
2020-05-02 11:26:00 Results found that osteocyte TSC1 disruption reduced sclerostin in bone, leading to osteosclerosis with enhanced bone formation in mice. TSC1 promotes sclerostin expression and prevents osteogenesis through inhibition of mTORC1 and downregulation of Sirt1. 31088250
2020-05-02 10:06:00 Loss of the tumor suppressor tuberous sclerosis complex 1 (Tsc1) in the liver promotes gluconeogenesis and glucose intolerance. 31919282

名称对应

Type IDs
Gene
UniProtKB-ID: TSC1_MOUSE
UniprotKB: Q9EP53
UniParc: UPI00000E5D6E, UPI00000229FE, UPI00005AC655, UPI000019B046
EMBL: AJ271912, AB047561, CH466542, AJ271911, AK147428, AL731851, AK122229, BC052399
Ensembl: ENSMUSG00000026812
KO: mmu:64930
Nucleutide sequences
EMBL-CDS: BAE27905.1, BAB60810.1, BAC65511.1, EDL08392.1, AAH52399.1, CAC20676.1, CAC20677.1
Ensembl_TRS: ENSMUST00000113869, ENSMUST00000028155, ENSMUST00000113870, ENSMUST00000113867
Protein sequencees
Ensembl_PRO: ENSMUSP00000109501, ENSMUSP00000109500, ENSMUSP00000109498, ENSMUSP00000028155
RefSeq: XP_036018339.1, XP_006498285.1, XP_006498284.1, XP_011237444.1, XP_006498283.1, XP_030107795.1, NP_001276504.1, XP_011237445.1, NP_001276505.1, XP_006498286.1, XP_011237446.1, NP_075025.2, XP_030107796.1
Others
UniRef100: UniRef100_Q9EP53
UniRef90: UniRef90_Q9EP53
UniRef50: UniRef50_Q92574
UniGene: Mm.224354
CCDS: CCDS79762.1, CCDS15844.1, CCDS71013.1

全选

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