| Type | Description |
|---|---|
| Definition | STIL centriolar assembly protein |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex. | 31754215 |
| 2020-08-29 12:45:00 | Knockdown of STIL suppresses the progression of gastric cancer by down-regulating the IGF-1/PI3K/AKT pathway. | 31187582 |
| 2020-05-16 12:22:00 | these results demonstrate that SFI1 is a centrosomal protein that localizes USP9X to the centrosome to stabilize STIL and promote centriole duplication. We propose that the USP9X protection of STIL to facilitate centriole duplication underlies roles of both proteins in human neurodevelopment. | 31197030 |
| 2020-03-14 10:49:00 | STIL is a key regulator that promotes the proliferation of nasopharyngeal carcinoma | 31607137 |
| 2019-11-09 13:04:00 | The conserved short coiled-coil region of STIL binds to and protects Plk4 from protein degradation at the site of procentriole formation. On the other hand, the conserved C-terminal region of STIL named truncated in microcephaly (TIM) domain promotes autophosphorylation and degradation of adjacent Plk4 by the direct interaction. | 29898389 |
| Type | IDs |
|---|---|
| Synonymous | MCPH7, SIL |
| Gene |
UniProtKB-ID:
STIL_HUMAN,
B7ZLW5_HUMAN,
A0A0A0MR87_HUMAN,
Q7Z626_HUMAN,
E9PSF2_HUMAN
UniprotKB:
Q15468,
B7ZLW5,
A0A0A0MR87,
Q7Z626,
E9PSF2
UniParc:
UPI00002042D9,
UPI0000470133,
UPI00001AAC41,
UPI000189A88B,
UPI00024D14DC,
UPI00002042D5
EMBL:
BC126223,
AF349649,
AF349650,
AF349657,
AF349645,
AF349652,
AF349656,
AF349648,
AF349651,
AF349653,
AF349646,
AF349644,
AF349654,
AL513322,
CR749851,
BC144089,
AL135960,
BC053615,
M74558,
AF349647,
AF349642,
AF349643,
AF349655
Ensembl:
ENSG00000123473
KO:
hsa:6491
|
| Nucleutide sequences |
EMBL-CDS:
CAI19733.1,
AAK51418.1,
CAH18699.1,
AAA60550.1,
CAI13468.1,
AAI26224.1,
AAI44090.1,
AAH53615.1
Ensembl_TRS:
ENST00000360380,
ENST00000371877,
ENST00000337817,
ENST00000396221
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360944,
ENSP00000353544,
ENSP00000337367,
ENSP00000379523
RefSeq:
NP_001269866.1,
XP_016857615.1,
XP_016857612.1,
NP_001269865.1,
XP_016857616.1,
NP_001041631.1,
XP_011540293.1,
XP_011540300.1,
XP_011540303.1,
XP_011540294.1,
XP_006710897.1,
XP_016857614.1,
XP_011540296.1,
NP_001364346.1,
NP_003026.2,
NP_001269868.1,
NP_001269867.1,
XP_016857613.1
|
| Others |
UniRef100:
UniRef100_Q15468,
UniRef100_E9PSF2,
UniRef100_B7ZLW5,
UniRef100_Q7Z626,
UniRef100_A0A0A0MR87
UniRef90:
UniRef90_Q15468,
UniRef90_Q7Z626,
UniRef90_Q15468-2
UniRef50:
UniRef50_Q7Z626,
UniRef50_Q15468
UniGene:
Hs.525198
CCDS:
CCDS548.1,
CCDS41329.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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