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64866 CDCP1

64866

CDCP1

CUB domain containing protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition CUB domain containing protein 1

研究结论

Date Results Publications
2021-03-20 13:35:00 Identification of CD318, and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma. 33674603
2021-02-02 13:24:00 CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo. 32250342
2020-10-03 12:52:00 Effect of NLK on the proliferation and invasion of laryngeal carcinoma cells by regulating CDCP1. 31364124
2020-05-16 10:22:00 CD318 expression may serve as novel prognostic factor depending on implemented therapy in acute myeloid leukemia patients 31965270
2020-04-25 10:06:00 Detailed cell fractionation, immunoprecipitation, microscopy, and immunohistochemical analyses demonstrated that CDCP1 promotes translocation of the key regulators of Wnt signaling, b-catenin, and E-cadherin, to the nucleus. Of functional importance, disruption of CDCP1 reduces nuclear localized, chromatin-associated b-catenin and nuclear localized E-cadherin, increases sequestration of these proteins in cell membranes 31471585

名称对应

Type IDs
Synonymous CD318, SIMA135, TRASK
Gene
UniProtKB-ID: CDCP1_HUMAN
UniprotKB: Q9H5V8
UniParc: UPI0001EC963B, UPI000013E304, UPI000004C62C
EMBL: AK023834, AC104165, BC069254, AC105902, BC021099, AY358779, AF468010, AY026461, AY375452, AK026187, AK026622, AY167484
Ensembl: ENSG00000163814
KO: hsa:64866
Nucleutide sequences
EMBL-CDS: BAB14695.1, AAO33397.1, AAK02058.1, BAB15388.1, AAO34538.1, AAH21099.1, AAR21289.1, AAQ89139.1, AAH69254.1, BAB15511.1
Gene_ORFName: UNQ2486/PRO5773
Ensembl_TRS: ENST00000425231, ENST00000296129
Protein sequencees
Ensembl_PRO: ENSP00000296129, ENSP00000399342
RefSeq: XP_011532326.1, XP_024309486.1, NP_835488.1, NP_073753.3, XP_016862559.1
Others
UniRef100: UniRef100_Q9H5V8
UniRef90: UniRef90_Q9H5V8
UniRef50: UniRef50_Q9H5V8
UniGene: Hs.476093
CCDS: CCDS46812.1, CCDS2727.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of California

10
2

National Cancer Center Research Institute

7
3

University of Tübingen

4
4

Osaka University Graduate School of Medicine

4
5

University of Toronto

3
热点人员
排名 研究人员 文献
1

John D Hooper

8
2

Ryuichi Sakai

8
3

Takamasa Uekita

8
4

Mark M Moasser

7
5

Yaowu He

6
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