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64857 PLEKHG2

64857

PLEKHG2

pleckstrin homology and RhoGEF domain containing G2

protein-coding

Homo sapiens

基因描述

Type Description
Definition pleckstrin homology and RhoGEF domain containing G2

研究结论

Date Results Publications
2020-04-11 12:41:00 results suggest that FHL1A specifically interacts with PLEKHG2 to regulate a function of PLEKHG2 that is modified by the interaction of Gbetagamma and Galphas. 28489964
2017-12-02 11:25:00 This is the first report to show that PLEKHG2 is a novel effector of Galphas, and is negatively regulated by the Galphas subunit through direct interaction. 28108261
2017-05-27 10:14:00 results provide evidence that FHL1A interacts with PLEKHG2 and regulates cell morphological change through the activity of PLEKHG2. 27765816
2016-10-22 11:27:00 Role of PLEKHG2 in actin polymerization and clinical and radiological findings in PLEKHG2 deficiency. 26573021
2015-08-29 10:43:00 Autoantibodies binding to Plekhg2 were found in 19 of 29 patients (66%) with active mycobacterial infections. 25213431

名称对应

Type IDs
Synonymous ARHGEF42, CLG, CTB-60E11.4, LDAMD
Gene
UniProtKB-ID: PKHG2_HUMAN
UniprotKB: Q9H7P9
UniParc: UPI00001C2028, UPI000059D71F, UPI0001AE644F
EMBL: BC075858, AK026111, AC011500, BC015174, AK024429, CH471126, BC013426
Ensembl: ENSG00000090924
KO: hsa:64857
Nucleutide sequences
EMBL-CDS: EAW56888.1, AAH15174.1, BAB15719.1, AAH75858.1, AAH13426.2, BAB15364.1
Ensembl_TRS: ENST00000409797, ENST00000425673
Protein sequencees
Ensembl_PRO: ENSP00000386492, ENSP00000392906
RefSeq: NP_073746.2, XP_006723397.1, XP_011525534.1, XP_016882640.1, NP_001338623.1, XP_016882639.1, XP_005259220.1, NP_001338622.1
Others
UniRef100: UniRef100_Q9H7P9
UniRef90: UniRef90_Q9H7P9
UniRef50: UniRef50_Q9H7P9
UniGene: Hs.631574
CCDS: CCDS86766.1, CCDS33022.2

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Gifu University

7
2

Institute for Research in Biomedicine (IRB Barcelona)

2
3

McGill University

2
4

University of Toronto

2
5

Dana-Farber Cancer Institute

2
热点人员
排名 研究人员 文献
1

Takahiro Nagase

9
2

Hiroshi Ueda

8
3

Katsuya Sato

7
4

Yukio Kitade

4
5

Masashi Nishikawa

3
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