| Type | Description |
|---|---|
| Definition | family with sequence similarity 129 member B |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | Structural Insight on Functional Regulation of Human MINERVA Protein. | 33142954 |
| 2020-01-11 10:50:00 | We have demonstrated that FAM129B in cancer promotes Nrf2 activity by reducing its ubiquitination through competition with Nrf2 for Keap1 binding via its DLG and ETGE motifs. In addition, FAM129B reduces chemosensitivity by augmenting Nrf2 antioxidative signaling and confers poor prognosis in breast and lung cancer | 31262713 |
| 2016-06-28 10:56:00 | activated EGFR phosphorylates the Y593 residue of the protein known as family with sequence similarity 129, member B (FAM129B), which is overexpressed in many types of human cancer. | 26721396 |
| 2011-06-18 10:56:00 | The rapid induction of apoptosis in FAM129B knockdown cells was reversed by co-transfection with recombinant FAM129B, indicating that its effect on apoptosis was specific. | 21148485 |
| 2010-01-21 00:00:00 | Phosphorylation of FAM129B has a role in controlling melanoma cell invasion. | 19362540 |
| Type | IDs |
|---|---|
| Synonymous | C9orf88, MEG-3, MINERVA, OC58, bA356B19.6 |
| Gene |
UniProtKB-ID:
NIBA2_HUMAN,
A0A024R872_HUMAN
UniprotKB:
Q96TA1,
A0A024R872
UniParc:
UPI0000130070,
UPI00001592F0
EMBL:
AL137555,
AF151783,
BC001979,
AF192911,
AL390116,
AL445222,
AB210016,
CH471090
Ensembl:
ENSG00000136830
KO:
hsa:64855
|
| Nucleutide sequences |
EMBL-CDS:
AAH01979.2,
EAW87675.1,
AAK57556.1,
CAB70809.1,
EAW87677.1,
BAE06098.1,
AAQ13825.1,
EAW87678.1
Gene_ORFName:
hCG_17928
Ensembl_TRS:
ENST00000373312,
ENST00000373314
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362409,
ENSP00000362411
RefSeq:
NP_001030611.1,
XP_005252192.2,
NP_073744.2,
XP_011517227.1
|
| Others |
UniRef100:
UniRef100_Q96TA1,
UniRef100_A0A024R872
UniRef90:
UniRef90_Q96TA1
UniRef50:
UniRef50_Q96TA1
UniGene:
Hs.522401
CCDS:
CCDS35144.1,
CCDS35145.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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