| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 46 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:10:00 | Data indicate a mechanism of USP46 regulation in renal cell carcinoma (RCC), and that USP46 is a tumor suppressor in RCC via proto-oncogene protein Akt (AKT) signaling pathway inactivation. | 31542232 |
| 2019-05-18 12:06:00 | The deubiquitinase USP46 is essential for proliferation and tumor growth of HPV-transformed cancers. | 30415951 |
| 2016-04-02 10:41:00 | Results suggest role for USP46/USP12 in Epstein-Barr virus induced growth transformation. | 25855980 |
| 2013-06-08 12:40:00 | USP46-mediated stabilization of PHLPP and the subsequent inhibition of Akt. | 22391563 |
| 2011-11-12 12:17:00 | results suggest that the USP46 gene might play a role in the pathophysiology of major depressive disorder in the Japanese population. | 21663972 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP46_HUMAN
UniprotKB:
P62068
UniParc:
UPI0001A61558,
UPI0001914BCD,
UPI0000006C18,
UPI00001F2CEA
EMBL:
AK302438,
CH471057,
BC037574,
AK296493,
GU455414,
AK022614,
AK024318,
AK299883
Ensembl:
ENSG00000109189
KO:
hsa:64854
|
| Nucleutide sequences |
EMBL-CDS:
AAH37574.1,
EAX05435.1,
BAB14133.1,
BAH13161.1,
ADV57651.1,
BAH13709.1,
BAH12373.1,
BAB14881.1
Ensembl_TRS:
ENST00000508499,
ENST00000441222
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407818,
ENSP00000423244
RefSeq:
NP_001273696.1,
XP_016864046.1,
NP_001273697.1,
NP_073743.2,
NP_001127695.1
|
| Others |
UniRef100:
UniRef100_P62068
UniRef90:
UniRef90_P62068
UniRef50:
UniRef50_P62068
UniGene:
Hs.7966
CCDS:
CCDS47053.1,
CCDS47054.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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