| Type | Description |
|---|---|
| Definition | YTH domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | [LIM-domain binding protein 2 regulated by m(6)A modification inhibits lung adenocarcinoma cell proliferation in vitro]. | 33849822 |
| 2021-03-13 13:15:00 | m(6) A RNA methylation regulators contribute to malignant progression in rectal cancer. | 32043594 |
| 2020-10-31 13:15:00 | Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population. | 32047883 |
| 2020-06-06 11:14:00 | The (6)-methyladenosine (m(6)A) binding pocket is conserved in YTH domain of ATP-dependent RNA helicase YTHDC2 (YTHDC2). | 31472957 |
| 2018-09-29 10:37:00 | YTHDC2 was recently found to promote a "fast-track" expression program for specific mRNAs, and our data suggest that YTHDC2 accomplishes this by recruitment of the RNA degradation machinery to regulate the stability of m(6)A-containing mRNAs and by utilizing its distinct RNA-binding domains to bridge interactions between m(6)A-containing mRNAs and the ribosomes to facilitate their efficient translation. | 29970596 |
| Type | IDs |
|---|---|
| Synonymous | CAHL, hYTHDC2 |
| Gene |
UniProtKB-ID:
YTDC2_HUMAN
UniprotKB:
Q9H6S0
UniParc:
UPI0000367311
EMBL:
AC093208,
AC010389,
AK025593,
BC137285
Ensembl:
ENSG00000047188
KO:
hsa:64848
|
| Nucleutide sequences |
EMBL-CDS:
AAI37286.1,
BAB15183.1
Ensembl_TRS:
ENST00000161863
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000161863
RefSeq:
XP_011541884.1,
NP_073739.3,
XP_016865222.1,
NP_001332904.1,
XP_016865220.1,
XP_011541883.1,
XP_016865224.1,
XP_011541888.1,
NP_001332905.1
|
| Others |
UniRef100:
UniRef100_Q9H6S0
UniRef90:
UniRef90_Q9H6S0
UniRef50:
UniRef50_Q9H6S0
UniGene:
Hs.231942
CCDS:
CCDS4113.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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