| Type | Description |
|---|---|
| Definition | complexin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:46:00 | Complexin I knockout rats exhibit a complex neurobehavioral phenotype including profound ataxia and marked deficits in lifespan. | 31875236 |
| 2019-03-30 11:53:00 | complexin-1 competes with alphaSNAP binding to the SNARE complex. | 29985126 |
| 2018-12-22 11:54:00 | actively drives SNARE complexes into linker-open conformation | 30194295 |
| 2018-03-31 11:55:00 | Results suggest that the C-terminal domain of Cplx1 plays a role in preferential membrane localization of Cpx to synaptic vesicles and find it as an important regulator for synaptic vesicle fusion through promoting Ca2+ in conjunction with SNAREs and synaptotagmins. | 27821736 |
| 2015-06-20 12:46:00 | Munc18a does not alter synaptic fusion rates mediated by neuronal SNAREs, synaptotagmin-1, and complexin-1. | 25716318 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CPLX1_RAT
UniprotKB:
P63041
UniParc:
UPI000002996A
EMBL:
U35098,
D70817,
BC093605
Ensembl:
ENSRNOG00000000060
KO:
rno:64832
|
| Nucleutide sequences |
EMBL-CDS:
AAC52270.1,
BAA11097.1,
AAH93605.1
Ensembl_TRS:
ENSRNOT00000061720
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000058432
RefSeq:
XP_006250633.1,
NP_074055.1
|
| Others |
UniRef100:
UniRef100_P63040
UniRef90:
UniRef90_P63040
UniRef50:
UniRef50_O14810
UniGene:
Rn.10133
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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