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6483 ST3GAL2

6483

ST3GAL2

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ST3 beta-galactoside alpha-2,3-sialyltransferase 2

研究结论

Date Results Publications
2017-08-19 12:23:00 Data suggest that ganglioside glycosyltransferases ST3GAL5, ST8SIA1, and B4GALNT1 are S-acylated at conserved cysteine residues located close to cytoplasmic border of their transmembrane domains; ST3Gal-II is acylated at conserved cysteine residue in N-terminal cytoplasmic tail; for B4GALNT1 and ST3Gal-II, dimer formation controls their S-acylation status. 28698248
2015-09-26 13:16:00 This suggests that the C-terminal domain of ST3Gal-II depends on N-glycosylation to attain an optimum conformation for proper exit from the endoplasmic reticulum 25916169
2010-01-21 00:00:00 Genomic structure, expression, and transcriptional regulation of ST3GALII. 12504121
2010-01-21 00:00:00 ST3Gal II is a MSGb5 (stage-specific embryonic antigen-4) synthase and its increased expression level is closely related to renal carcinogenesis 12716912

名称对应

Type IDs
Synonymous Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2
Gene
UniProtKB-ID: SIA4B_HUMAN, B3KXG9_HUMAN, A0A024QZA4_HUMAN
UniprotKB: Q16842, B3KXG9, A0A024QZA4
UniParc: UPI00005A8279, UPI0000001C5C
EMBL: U63090, X96667, AK127322, CH471241, BC036777
Ensembl: ENSG00000157350
KO: hsa:6483
Nucleutide sequences
EMBL-CDS: AAH36777.1, CAA65447.1, AAB40389.1, BAG54481.1, EAW51820.1, EAW51821.1, EAW51818.1, EAW51819.1
Gene_ORFName: hCG_32368
Ensembl_TRS: ENST00000342907, ENST00000393640
Protein sequencees
Ensembl_PRO: ENSP00000377257, ENSP00000345477
RefSeq: NP_008858.1
Others
UniRef100: UniRef100_Q16842, UniRef100_B3KXG9
UniRef90: UniRef90_Q16842
UniRef50: UniRef50_Q16842
UniGene: Hs.368611
CCDS: CCDS10890.1

全选

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